Strong, Roland K.

Lipocalin 2 mediates an innate immune response to bacterial infection by sequestrating iron

Flo, T. H., Smith, K. D., Sato, S., Rodriguez, D. J., Holmes, M. A., Strong, R. K., Akira, S., & Aderem, A. (2004) · Nature

Iron Metabolism and DisordersImmune Response and Inflammation

Cited by 1,877

The Neutrophil Lipocalin NGAL Is a Bacteriostatic Agent that Interferes with Siderophore-Mediated Iron Acquisition

Goetz, D. H., Holmes, M. A., Borregaard, N., Bluhm, M. E., Raymond, K. N., & Strong, R. K. (2002) · Molecular Cell

Antimicrobial Peptides and ActivitiesIron Metabolism and Disorders

Cited by 1,355

An Iron Delivery Pathway Mediated by a Lipocalin

Yang, J., Goetz, D., Li, J.-Y., Wang, W., Mori, K., Setlik, D., Du, T., Erdjument-Bromage, H., Tempst, P., Strong, R., et al. (2002) · Molecular Cell

Iron Metabolism and DisordersTrace Elements in Health

Cited by 651

Proof of principle for epitope-focused vaccine design

Correia, B. E., Bates, J. T., Loomis, R. J., Baneyx, G., Carrico, C., Jardine, J. G., Rupert, P., Correnti, C., Kalyuzhniy, O., Vittal, V., et al. (2014) · Nature

vaccines and immunoinformatics approachesSARS-CoV-2 and COVID-19 Research

Cited by 555

Lipocalin 2 promotes breast cancer progression

Yang, J., Bielenberg, D. R., Rodig, S. J., Doiron, R., Clifton, M. C., Kung, A. L., Strong, R. K., Zurakowski, D., & Moses, M. A. (2009) · Proceedings of the National Academy of Sciences

Cancer Cells and MetastasisMechanisms of cancer metastasis

Cited by 356

The pathogen-associated iroA gene cluster mediates bacterial evasion of lipocalin 2

Fischbach, M. A., Lin, H., Zhou, L., Yu, Y., Abergel, R. J., Liu, D. R., Raymond, K. N., Wanner, B. L., Strong, R. K., Walsh, C. T., et al. (2006) · Proceedings of the National Academy of Sciences

Escherichia coli research studiesBacterial Genetics and Biotechnology

Cited by 319

Iron traffics in circulation bound to a siderocalin (Ngal)–catechol complex

Bao, G., Clifton, M., Hoette, T. M., Mori, K., Deng, S.-X., Qiu, A., Viltard, M., Williams, D., Paragas, N., Leete, T., et al. (2010) · Nature Chemical Biology

Iron Metabolism and DisordersHemoglobin structure and function

Cited by 307

Siderocalin (Lcn 2) Also Binds Carboxymycobactins, Potentially Defending against Mycobacterial Infections through Iron Sequestration

Holmes, M. A., Paulsene, W., Jide, X., Ratledge, C., & Strong, R. K. (2005) · Structure

Iron Metabolism and DisordersTuberculosis Research and Epidemiology

Cited by 246

Computation-Guided Backbone Grafting of a Discontinuous Motif onto a Protein Scaffold

Azoitei, M. L., Correia, B. E., Ban, Y.-E. A., Carrico, C., Kalyuzhniy, O., Chen, L., Schroeter, A., Huang, P.-S., McLellan, J. S., Kwong, P. D., et al. (2011) · Science

Protein Structure and DynamicsBiochemical and Structural Characterization

Cited by 224

Anthrax pathogen evades the mammalian immune system through stealth siderophore production

Abergel, R. J., Wilson, M. K., Arceneaux, J. E. L., Hoette, T. M., Strong, R. K., Byers, B. R., & Raymond, K. N. (2006) · Proceedings of the National Academy of Sciences

Bacillus and Francisella bacterial researchBacterial Genetics and Biotechnology

Cited by 198

Mammalian Siderophores, Siderophore-binding Lipocalins, and the Labile Iron Pool

Correnti, C., & Strong, R. K. (2012) · Journal of Biological Chemistry

Iron Metabolism and DisordersHemoglobin structure and function

Cited by 115

Intracellular Mycobacterium avium Intersect Transferrin in the Rab11+Recycling Endocytic Pathway and Avoid Lipocalin 2 Trafficking to the Lysosomal Pathway

Halaas, Ø., Steigedal, M., Haug, M., Awuh, J. A., Ryan, L., Brech, A., Sato, S., Husebye, H., Cangelosi, G. A., Akira, S., et al. (2010) · The Journal of Infectious Diseases

Mycobacterium research and diagnosisTuberculosis Research and Epidemiology

Cited by 68

Immune Interference in Mycobacterium tuberculosis Intracellular Iron Acquisition through Siderocalin Recognition of Carboxymycobactins

Hoette, T. M., Clifton, M. C., Zawadzka, A. M., Holmes, M. A., Strong, R. K., & Raymond, K. N. (2011) · ACS Chemical Biology

Tuberculosis Research and EpidemiologyIron Metabolism and Disorders

Cited by 31