Tsang, Stephen H.

Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes.

White, J. K., Gerdin, A.-K., Karp, N. A., Ryder, E., Buljan, M., Bussell, J. N., Salisbury, J., Clare, S., Ingham, N. J., Podrini, C., et al. (2013) · Cell

Genomics and Rare DiseasesAnimal Genetics and Reproduction

Cited by 509

Allele-Specific Chromosome Removal after Cas9 Cleavage in Human Embryos

Zuccaro, M. V., Xu, J., Mitchell, C., Marin, D., Zimmerman, R., Rana, B., Weinstein, E., King, R. T., Palmerola, K. L., Smith, M. E., et al. (2020) · Cell

CRISPR and Genetic EngineeringDNA Repair Mechanisms

Cited by 303

Viral Delivery Systems for CRISPR

Xu, C. L., Ruan, M. Z. C., Mahajan, V. B., & Tsang, S. H. (2019) · Viruses

CRISPR and Genetic EngineeringVirus-based gene therapy research

Cited by 277

Safety and Vision Outcomes of Subretinal Gene Therapy Targeting Cone Photoreceptors in Achromatopsia: A Nonrandomized Controlled Trial

Fischer, M. D., Michalakis, S., Wilhelm, B., Zobor, D., Muehlfriedel, R., Kohl, S., Weisschuh, N., Ochakovski, G. A., Klein, R., Schoen, C., et al. (2020) · JAMA Ophthalmology

Retinal Development and DisordersVirus-based gene therapy research

Cited by 177

Gene therapy and genome surgery in the retina

DiCarlo, J. E., Mahajan, V. B., & Tsang, S. H. (2018) · Journal of Clinical Investigation

Retinal Development and DisordersVirus-based gene therapy research

Cited by 127

Clustered Regularly Interspaced Short Palindromic Repeats-Based Genome Surgery for the Treatment of Autosomal Dominant Retinitis Pigmentosa

Tsai, Y.-T., Wu, W.-H., Lee, T.-T., Wu, W.-P., Xu, C. L., Park, K. S., Cui, X., Justus, S., Lin, C.-S., Jauregui, R., et al. (2018) · Ophthalmology

Retinal Development and DisordersVirus-based gene therapy research

Cited by 119

Precision Medicine: Personalized Proteomics for the Diagnosis and Treatment of Idiopathic Inflammatory Disease

Velez, G., Roybal, C. N., Colgan, D., Tsang, S. H., Bassuk, A. G., & Mahajan, V. B. (2016) · JAMA Ophthalmology

Ocular Diseases and Behçet’s SyndromeVasculitis and related conditions

Cited by 66

Autosomal Dominant Retinitis Pigmentosa

Tsang, S. H., & Sharma, T. (2018) · Advances in Experimental Medicine and Biology

Retinal Development and DisordersGenetic and Kidney Cyst Diseases

Cited by 53

Effects of deficiency in the RLBP1-encoded visual cycle protein CRALBP on visual dysfunction in humans and mice

Lima de Carvalho, J. R., Kim, H. J., Ueda, K., Zhao, J., Owji, A. P., Yang, T., Tsang, S. H., & Sparrow, J. R. (2020) · Journal of Biological Chemistry

Retinal Development and DisordersRetinal Diseases and Treatments

Cited by 42

New syndrome with retinitis pigmentosa is caused by nonsense mutations in retinol dehydrogenase RDH11

Xie, Y. (., Lee, W., Cai, C., Gambin, T., Nõupuu, K., Sujirakul, T., Ayuso, C., Jhangiani, S., Muzny, D., Boerwinkle, E., et al. (2014) · Human Molecular Genetics

Retinal Development and DisordersRetinoids in leukemia and cellular processes

Cited by 40

Peripapillary sparing in RDH12-associated Leber congenital amaurosis

Garg, A., Lee, W., Sengillo, J. D., Allikmets, R., Garg, K., & Tsang, S. H. (2017) · Ophthalmic Genetics

Retinal Development and DisordersRetinal Diseases and Treatments

Cited by 27

Perspectives on Gene Therapy: Choroideremia Represents a Challenging Model for the Treatment of Other Inherited Retinal Degenerations

MacDonald, I. M., Moen, C., Duncan, J. L., Tsang, S. H., Cehajic-Kapetanovic, J., & Aleman, T. S. (2020) · Translational Vision Science & Technology

Retinal Development and DisordersVirus-based gene therapy research

Cited by 20

Short-Wavelength and Near-Infrared Autofluorescence in Patients with Deficiencies of the Visual Cycle and Phototransduction

Oh, J. K., Lima de Carvalho, J. R., Ryu, J., Tsang, S. H., & Sparrow, J. R. (2020) · Scientific Reports

Retinal Development and DisordersRetinal Diseases and Treatments

Cited by 18

VITAMIN A DEFICIENCY MONITORED BY QUANTITATIVE SHORT WAVELENGTH FUNDUS AUTOFLUORESCENCE IN A CASE OF BARIATRIC SURGERY

Lima de Carvalho, J. R., Tsang, S. H., & Sparrow, J. R. (2022) · RETINAL Cases & Brief Reports

Retinal Development and DisordersRetinal Diseases and Treatments

Cited by 14

Vitamin A deficiency in New York City

Braunstein, A., Trief, D., Wang, N.-K., Chang, S., & Tsang, S. H. (2010) · The Lancet

Retinal Development and DisordersRetinoids in leukemia and cellular processes

Cited by 9

CRISPR off-target analysis platforms

Xu, C. L., Ruan, M. Z., Ragi, S. D., & Tsang, S. H. (2023) · Methods in molecular biology

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 6