Crowther, R. A.

Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease

Goedert, M., Spillantini, M. G., Jakes, R., Rutherford, D., & Crowther, R. A. (1989) · Neuron

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 2,492

Cryo-EM structures of tau filaments from Alzheimer’s disease

Fitzpatrick, A. W. P., Falcon, B., He, S., Murzin, A. G., Murshudov, G., Garringer, H. J., Crowther, R. A., Ghetti, B., Goedert, M., & Scheres, S. H. W. (2017) · Nature

Alzheimer's disease research and treatmentsAdvanced Electron Microscopy Techniques and Applications

Cited by 2,061

Transmission and spreading of tauopathy in transgenic mouse brain

Clavaguera, F., Bolmont, T., Crowther, R. A., Abramowski, D., Frank, S., Probst, A., Fraser, G., Stalder, A. K., Beibel, M., Staufenbiel, M., et al. (2009) · Nature Cell Biology

Alzheimer's disease research and treatmentsAmyotrophic Lateral Sclerosis Research

Cited by 1,803

Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: identification as the microtubule-associated protein tau

Goedert, M., Wischik, C. M., Crowther, R. A., Walker, J. E., & Klug, A. (1988) · Proceedings of the National Academy of Sciences

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 1,134

Cloning and sequencing of the cDNA encoding an isoform of microtubule‐associated protein tau containing four tandem repeats: differential expression of tau protein mRNAs in human brain.

Goedert, M., Spillantini, M. G., Potier, M. C., Ulrich, J., & Crowther, R. A. (1989) · The EMBO Journal

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 1,037

Assembly of microtubule-associated protein tau into Alzheimer-like filaments induced by sulphated glycosaminoglycans

Goedert, M., Jakes, R., Spillantini, M. G., Hasegawa, M., Smith, M. J., & Crowther, R. A. (1996) · Nature

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 1,036

Propagation of Tau aggregates and neurodegeneration

Goedert, M., Eisenberg, D. S., & Crowther, R. A. (2017) · Annual Review of Neuroscience

Alzheimer's disease research and treatmentsPrion Diseases and Protein Misfolding

Cited by 632

The abnormal phosphorylation of tau protein at Ser-202 in Alzheimer disease recapitulates phosphorylation during development.

Goedert, M., Jakes, R., Crowther, R. A., Six, J., Lübke, U., Vandermeeren, M., Cras, P., Trojanowski, J. Q., & Lee, V. M. (1993) · Proceedings of the National Academy of Sciences

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 446

Epitope mapping of monoclonal antibodies to the paired helical filaments of Alzheimer's disease: identification of phosphorylation sites in tau protein

Goedert, M., Jakes, R., Crowther, R. A., Cohen, P., Vanmechelen, E., Vandermeeren, M., & Cras, P. (1994) · Biochemical Journal

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 375

Tau Mutations Cause Frontotemporal Dementias

Goedert, M., Crowther, R. A., & Spillantini, M. G. (1998) · Neuron

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 268

Tau Proteins and Neurofibrillary Degeneration

Goedert, M., Spillantini, M. G., & Crowther, R. A. (1991) · Brain Pathology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 178

Comparison of the neurofibrillary pathology in Alzheimer’s disease and familial presenile dementia with tangles

Spillantini, M. G., Crowther, R. A., & Goedert, M. (1996) · Acta Neuropathologica

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 160

Abnormally phosphorylated tau is associated with neuronal and axonal loss in experimental autoimmune encephalomyelitis and multiple sclerosis

Anderson, J. M., Hampton, D. W., Patani, R., Pryce, G., Crowther, R. A., Reynolds, R., Franklin, R. J. M., Giovannoni, G., Compston, D. A. S., Baker, D., et al. (2008) · Brain

Multiple Sclerosis Research StudiesAlzheimer's disease research and treatments

Cited by 141

Functional effects of tau gene mutations ΔN296 and N296H

Yoshida, H., Crowther, R. A., & Goedert, M. (2002) · Journal of Neurochemistry

Alzheimer's disease research and treatmentsAmyotrophic Lateral Sclerosis Research

Cited by 56