Trempe, Jean-François

The inner junction complex of the cilia is an interaction hub that involves tubulin post-translational modifications

Khalifa, A. A. Z., Ichikawa, M., Dai, D., Kubo, S., Black, C. S., Peri, K., McAlear, T. S., Veyron, S., Yang, S. K., Vargas, J., et al. (2020) · eLife

Genetic and Kidney Cyst DiseasesMicrotubule and mitosis dynamics

Cited by 1,676

Ubiquitin is phosphorylated by PINK1 to activate parkin

Koyano, F., Okatsu, K., Kosako, H., Tamura, Y., Go, E., Kimura, M., Kimura, Y., Tsuchiya, H., Yoshihara, H., Hirokawa, T., et al. (2014) · Nature

Parkinson's Disease Mechanisms and TreatmentsUbiquitin and proteasome pathways

Cited by 1,477

TOM20 Gates PINK1 Activity And Mediates Its Tethering Of The TOM And TIM23 Translocases Upon Mitochondrial Stress

Eldeeb, M. A., Bayne, A. N., Fallahi, A., Goiran, T., MacDougall, E. J., Soumbasis, A., Zorca, C. E., Tabah, J.-J., Thomas, R. A., Karpilovsky, N., et al. (2023) · Proceedings of the National Academy of Sciences

Parkinson's Disease Mechanisms and TreatmentsAutophagy in Disease and Therapy

Cited by 77

GALC variants affect galactosylceramidase enzymatic activity and risk of Parkinson’s disease

Senkevich, K., Zorca, C. E., Dworkind, A., Rudakou, U., Somerville, E., Yu, E., Ermolaev, A., Nikanorova, D., Ahmad, J., Ruskey, J. A., et al. (2023) · Brain

Lysosomal Storage Disorders ResearchParkinson's Disease Mechanisms and Treatments

Cited by 40

The role of the individual TOM subunits in the association of PINK1 with depolarized mitochondria

Maruszczak, K. K., Jung, M., Rasool, S., Trempe, J.-F., & Rapaport, D. (2022) · Journal of Molecular Medicine

Mitochondrial Function and PathologyAutophagy in Disease and Therapy

Cited by 29

Crystal structure of human PACRG in complex with MEIG1 reveals roles in axoneme formation and tubulin binding

Khan, N., Pelletier, D., McAlear, T. S., Croteau, N., Veyron, S., Bayne, A. N., Black, C., Ichikawa, M., Khalifa, A. A. Z., Chaaban, S., et al. (2021) · Structure

Genetic and Kidney Cyst DiseasesMicrotubule and mitosis dynamics

Cited by 24