Muir, Tom W.

Inhibition of PRC2 Activity by a Gain-of-Function H3 Mutation Found in Pediatric Glioblastoma

Lewis, P. W., Müller, M. M., Koletsky, M. S., Cordero, F., Lin, S., Banaszynski, L. A., Garcia, B. A., Muir, T. W., Becher, O. J., & Allis, C. D. (2013) · Science

Glioma Diagnosis and TreatmentEpigenetics and DNA Methylation

Cited by 1,345

How many human proteoforms are there?

Aebersold, R., Agar, J. N., Amster, I. J., Baker, M. S., Bertozzi, C. R., Boja, E. S., Costello, C. E., Cravatt, B. F., Fenselau, C., Garcia, B. A., et al. (2018) · Nature Chemical Biology

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 907

Chemically ubiquitylated histone H2B stimulates hDot1L-mediated intranucleosomal methylation

McGinty, R. K., Kim, J., Chatterjee, C., Roeder, R. G., & Muir, T. W. (2008) · Nature

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 563

Inteins: nature's gift to protein chemists

Shah, N. H., & Muir, T. W. (2014) · Chem. Sci.

Biochemical and Structural CharacterizationClick Chemistry and Applications

Cited by 404

The expanding landscape of ‘oncohistone’ mutations in human cancers

Nacev, B. A., Feng, L., Bagert, J. D., Lemiesz, A. E., Gao, J., Soshnev, A. A., Kundra, R., Schultz, N., Muir, T. W., & Allis, C. D. (2019) · Nature

Chromatin Remodeling and CancerGenomics and Chromatin Dynamics

Cited by 384

Histones: At the Crossroads of Peptide and Protein Chemistry

Müller, M. M., & Muir, T. W. (2015) · Chemical Reviews

Chemical Synthesis and AnalysisGenomics and Chromatin Dynamics

Cited by 247

Strategy for “Detoxification” of a Cancer-Derived Histone Mutant Based on Mapping Its Interaction with the Methyltransferase PRC2

Brown, Z. Z., Müller, M. M., Jain, S. U., Allis, C. D., Lewis, P. W., & Muir, T. W. (2014) · Journal of the American Chemical Society

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 111

Extein Residues Play an Intimate Role in the Rate-Limiting Step of Protein Trans -Splicing

Shah, N. H., Eryilmaz, E., Cowburn, D., & Muir, T. W. (2013) · Journal of the American Chemical Society

Biochemical and Structural CharacterizationProtein Structure and Dynamics

Cited by 84

Targeted Histone Peptides: Insights into the Spatial Regulation of the Methyltransferase PRC2 by using a Surrogate of Heterotypic Chromatin

Brown, Z. Z., Müller, M. M., Kong, H. E., Lewis, P. W., & Muir, T. W. (2015) · Angewandte Chemie International Edition

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 17

A SWI/SNF-specific Ig-like domain, SWIFT, is a transcription factor binding platform

Jain, S. U., Williamson, K. E., Ying, A. W., Turner, A. M., Jiang, R. J., Raval, S., So, K., Allison, M. J., Sankar, A., Sáme Guerra, D. D., et al. (2026) · Science

Chromatin Remodeling and CancerGenomics and Chromatin Dynamics

Cited by 11