Orlicky, David J.

Triplication of the interferon receptor locus contributes to hallmarks of Down syndrome in a mouse model

Waugh, K. A., Minter, R., Baxter, J., Chi, C., Galbraith, M. D., Tuttle, K. D., Eduthan, N. P., Kinning, K. T., Andrysik, Z., Araya, P., et al. (2023) · Nature Genetics

Down syndrome and intellectual disability researchinterferon and immune responses

Cited by 117

Spaceflight Activates Lipotoxic Pathways in Mouse Liver

Jonscher, K. R., Alfonso-Garcia, A., Suhalim, J. L., Orlicky, D. J., Potma, E. O., Ferguson, V. L., Bouxsein, M. L., Bateman, T. A., Stodieck, L. S., Levi, M., et al. (2016) · PLOS ONE

Spaceflight effects on biologyMetabolomics and Mass Spectrometry Studies

Cited by 108

JAK1 Inhibition Blocks Lethal Immune Hypersensitivity in a Mouse Model of Down Syndrome

Tuttle, K. D., Waugh, K. A., Araya, P., Minter, R., Orlicky, D. J., Ludwig, M., Andrysik, Z., Burchill, M. A., Tamburini, B. A. J., Sempeck, C., et al. (2020) · Cell Reports

interferon and immune responsesDown syndrome and intellectual disability research

Cited by 72

Increased carbonylation of the lipid phosphatase PTEN contributes to Akt2 activation in a murine model of early alcohol-induced steatosis

Shearn, C. T., Smathers, R. L., Backos, D. S., Reigan, P., Orlicky, D. J., & Petersen, D. R. (2013) · Free Radical Biology and Medicine

Alcohol Consumption and Health EffectsLiver Disease Diagnosis and Treatment

Cited by 69

Identification of 5′ AMP-activated Kinase as a Target of Reactive Aldehydes during Chronic Ingestion of High Concentrations of Ethanol

Shearn, C. T., Backos, D. S., Orlicky, D. J., Smathers-McCullough, R. L., & Petersen, D. R. (2014) · Journal of Biological Chemistry

Alcohol Consumption and Health EffectsMetabolism, Diabetes, and Cancer

Cited by 57

Cytokine‐Producing B Cells Promote Immune‐Mediated Bile Duct Injury in Murine Biliary Atresia

Bednarek, J., Traxinger, B., Brigham, D., Roach, J., Orlicky, D., Wang, D., Pelanda, R., & Mack, C. L. (2018) · Hepatology

Pediatric Hepatobiliary Diseases and TreatmentsLiver Diseases and Immunity

Cited by 38

Ag-driven CD8+ T cell clonal expansion is a prominent feature of MASH in humans and mice

Burtis, A. E. C., DeNicola, D. M. C., Ferguson, M. E., Santos, R. G., Pinilla, C., Kriss, M. S., Orlicky, D. J., Tamburini, B. A. J., Gillen, A. E., & Burchill, M. A. (2025) · Hepatology

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 30

Increased 4-hydroxynonenal protein adducts in male GSTA4–4/PPAR-α double knockout mice enhance injury during early stages of alcoholic liver disease

Ronis, M. J. J., Mercer, K. E., Gannon, B., Engi, B., Zimniak, P., Shearn, C. T., Orlicky, D. J., Albano, E., Badger, T. M., & Petersen, D. R. (2015) · American Journal of Physiology-Gastrointestinal and Liver Physiology

Alcohol Consumption and Health EffectsLiver physiology and pathology

Cited by 27

Liver sinusoidal endothelial cells regulate the balance between hepatic immunosuppression and immunosurveillance

Kremer, K. N., Khammash, H. A., Miranda, A. M., Rutt, L. N., Twardy, S. M., Anton, P. E., Campbell, M. L., Garza-Ortiz, C., Orlicky, D. J., Pelanda, R., et al. (2025) · Frontiers in Immunology

Liver physiology and pathologyCancer Immunotherapy and Biomarkers

Cited by 19

Increased hepatocellular protein carbonylation in human end-stage alcoholic cirrhosis

Shearn, C. T., Orlicky, D. J., Saba, L. M., Shearn, A. H., & Petersen, D. R. (2015) · Free Radical Biology and Medicine

Alcohol Consumption and Health EffectsAntioxidant Activity and Oxidative Stress

Cited by 19