Backus, Keriann M.

Proteome-wide covalent ligand discovery in native biological systems

Backus, K. M., Correia, B. E., Lum, K. M., Forli, S., Horning, B. D., González-Páez, G. E., Chatterjee, S., Lanning, B. R., Teijaro, J. R., Olson, A. J., et al. (2016) · Nature

Click Chemistry and ApplicationsAdvanced Proteomics Techniques and Applications

Cited by 940

Global profiling of lysine reactivity and ligandability in the human proteome

Hacker, S. M., Backus, K. M., Lazear, M. R., Forli, S., Correia, B. E., & Cravatt, B. F. (2017) · Nature Chemistry

Click Chemistry and ApplicationsAdvanced Proteomics Techniques and Applications

Cited by 485

Chemical Proteomics Identifies Druggable Vulnerabilities in a Genetically Defined Cancer

Bar-Peled, L., Kemper, E. K., Suciu, R. M., Vinogradova, E. V., Backus, K. M., Horning, B. D., Paul, T. A., Ichu, T.-A., Svensson, R. U., Olucha, J., et al. (2017) · Cell

Genomics, phytochemicals, and oxidative stressLung Cancer Treatments and Mutations

Cited by 262

Uptake of unnatural trehalose analogs as a reporter for Mycobacterium tuberculosis

Backus, K. M., Boshoff, H. I., Barry, C. S., Boutureira, O., Patel, M. K., D'Hooge, F., Lee, S. S., Via, L. E., Tahlan, K., Barry, C. E., et al. (2011) · Nature Chemical Biology

Tuberculosis Research and EpidemiologyClick Chemistry and Applications

Cited by 237

Chemical proteomic map of dimethyl fumarate–sensitive cysteines in primary human T cells

Blewett, M. M., Xie, J., Zaro, B. W., Backus, K. M., Altman, A., Teijaro, J. R., & Cravatt, B. F. (2016) · Science Signaling

Click Chemistry and ApplicationsRedox biology and oxidative stress

Cited by 194

A Screen for Protein–Protein Interactions in Live Mycobacteria Reveals a Functional Link between the Virulence-Associated Lipid Transporter LprG and the Mycolyltransferase Antigen 85A

Touchette, M. H., Van Vlack, E. R., Bai, L., Kim, J., Cognetta, A. B., Previti, M. L., Backus, K. M., Martin, D. W., Cravatt, B. F., & Seeliger, J. C. (2017) · ACS Infectious Diseases

Tuberculosis Research and EpidemiologyBacterial Genetics and Biotechnology

Cited by 34

A solid-phase compatible silane-based cleavable linker enables custom isobaric quantitative chemoproteomics

Burton, N., Polasky, D., Shikwanna, F., Ofori, S., Yan, T., Geiszler, D., da Veiga Leprevost, F., Nesvizhskii, A., & Backus, K. (2023) · Journal of the American Chemical Society

Advanced Proteomics Techniques and ApplicationsClick Chemistry and Applications

Cited by 22

A solid-phase compatible silane-based cleavable linker enables custom isobaric quantitative chemoproteomics

Burton, N., Polasky, D., Shikwanna, F., Ofori, S., Yan, T., Geiszler, D., da Veiga Leprevost, F., Nesvizhskii, A., & Backus, K. (2023) · Journal of the American Chemical Society

Advanced Proteomics Techniques and ApplicationsClick Chemistry and Applications

Cited by 22

Solid-Phase Compatible Silane-Based Cleavable Linker Enables Custom Isobaric Quantitative Chemoproteomics

Burton, N. R., Polasky, D. A., Shikwana, F., Ofori, S., Yan, T., Geiszler, D. J., Veiga Leprevost, F. D., Nesvizhskii, A. I., & Backus, K. M. (2023) · Journal of the American Chemical Society

Advanced Proteomics Techniques and ApplicationsClick Chemistry and Applications

Cited by 22

Defining the Cell Surface Cysteinome using Two-step Enrichment Proteomics

Yan, T., Boatner, L. M., Cui, L., Tontonoz, P., & Backus, K. M. (2023) · JACS Au

Redox biology and oxidative stressAdvanced Proteomics Techniques and Applications

Cited by 21