O’Brien, Charles A.

Glucocorticoids Act Directly on Osteoclasts to Increase Their Life Span and Reduce Bone Density

Jia, D., O’Brien, C. A., Stewart, S. A., Manolagas, S. C., & Weinstein, R. S. (2006) · Endocrinology

Bone Metabolism and DiseasesBone health and osteoporosis research

Cited by 394

Osteocytes, not Osteoblasts or Lining Cells, are the Main Source of the RANKL Required for Osteoclast Formation in Remodeling Bone

Xiong, J., Piemontese, M., Onal, M., Campbell, J., Goellner, J. J., Dusevich, V., Bonewald, L., Manolagas, S. C., & O’Brien, C. A. (2015) · PLOS ONE

Bone Metabolism and DiseasesBone health and osteoporosis research

Cited by 323

Soluble RANKL contributes to osteoclast formation in adult mice but not ovariectomy-induced bone loss

Xiong, J., Cawley, K., Piemontese, M., Fujiwara, Y., Zhao, H., Goellner, J. J., & O’Brien, C. A. (2018) · Nature Communications

Bone Metabolism and DiseasesBone health and osteoporosis research

Cited by 144

Osteocyte RANKL is required for cortical bone loss with age and is induced by senescence

Kim, H.-N., Xiong, J., MacLeod, R. S., Iyer, S., Fujiwara, Y., Cawley, K. M., Han, L., He, Y., Thostenson, J. D., Ferreira, E., et al. (2020) · JCI Insight

Bone Metabolism and DiseasesBone health and osteoporosis research

Cited by 117

Local Production of Osteoprotegerin by Osteoblasts Suppresses Bone Resorption

Cawley, K. M., Bustamante-Gomez, N. C., Guha, A. G., MacLeod, R. S., Xiong, J., Gubrij, I., Liu, Y., Mulkey, R., Palmieri, M., Thostenson, J. D., et al. (2020) · Cell Reports

Bone Metabolism and DiseasesBone health and osteoporosis research

Cited by 114

Classical Genotropic Versus Kinase-Initiated Regulation of Gene Transcription by the Estrogen Receptor α

Almeida, M., Han, L., O’Brien, C. A., Kousteni, S., & Manolagas, S. C. (2006) · Endocrinology

Estrogen and related hormone effectsBreast Cancer Treatment Studies

Cited by 40