Ellis, James

Stage-Specific Optimization of Activin/Nodal and BMP Signaling Promotes Cardiac Differentiation of Mouse and Human Pluripotent Stem Cell Lines

Kattman, S. J., Witty, A. D., Gagliardi, M., Dubois, N. C., Niapour, M., Hotta, A., Ellis, J., & Keller, G. (2011) · Cell Stem Cell

Pluripotent Stem Cells ResearchCongenital heart defects research

Cited by 1,159

Correction of sickle cell disease in transgenic mouse models by gene therapy

Pawliuk, R., Westerman, K. A., Fabry, M. E., Payen, E., Tighe, R., Bouhassira, E. E., Acharya, S. A., Ellis, J., London, I. M., Eaves, C. J., et al. (2001) · Science

Virus-based gene therapy researchHemoglobinopathies and Related Disorders

Cited by 579

Silencing and Variegation of Gammaretrovirus and Lentivirus Vectors

Ellis, J. (2005) · Human Gene Therapy

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 379

Isolation of MECP2-null Rett Syndrome patient hiPS cells and isogenic controls through X-chromosome inactivation

Cheung, A. Y. L., Horvath, L. M., Grafodatskaya, D., Pasceri, P., Weksberg, R., Hotta, A., Carrel, L., & Ellis, J. (2011) · Human Molecular Genetics

Genetics and Neurodevelopmental DisordersPluripotent Stem Cells Research

Cited by 271

SHANK2 mutations associated with autism spectrum disorder cause hyperconnectivity of human neurons

Zaslavsky, K., Zhang, W.-B., McCready, F. P., Rodrigues, D. C., Deneault, E., Loo, C., Zhao, M., Ross, P. J., El Hajjar, J., Romm, A., et al. (2019) · Nature Neuroscience

Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research

Cited by 174

Complete disruption of autism-susceptibility genes by gene editing predominantly reduces functional connectivity of isogenic human neurons

Deneault, E., White, S. H., Rodrigues, D. C., Ross, P. J., Faheem, M., Zaslavsky, K., Wang, Z., Alexandrova, R., Pellecchia, G., Wei, W., et al. (2018) · Stem Cell Reports

Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research

Cited by 145

MECP2 Isoform-Specific Vectors with Regulated Expression for Rett Syndrome Gene Therapy

Rastegar, M., Hotta, A., Pasceri, P., Makarem, M., Cheung, A. Y. L., Elliott, S., Park, K. J., Adachi, M., Jones, F. S., Clarke, I. D., et al. (2009) · PLoS ONE

Virus-based gene therapy researchGenetics and Neurodevelopmental Disorders

Cited by 79

Optimizing neuronal differentiation from induced pluripotent stem cells to model ASD

Kim, D.-S., Ross, P. J., Zaslavsky, K., & Ellis, J. (2014) · Frontiers in Cellular Neuroscience

Pluripotent Stem Cells ResearchAutism Spectrum Disorder Research

Cited by 70