Hashimoto, Kenji

Splenic NKG2D confers resilience versus susceptibility in mice after chronic social defeat stress: beneficial effects of (R)-ketamine

Zhang, K., Sakamoto, A., Chang, L., Qu, Y., Wang, S., Pu, Y., Tan, Y., Wang, X., Fujita, Y., Ishima, T., et al. (2021) · European Archives of Psychiatry and Clinical Neuroscience

Stress Responses and CortisolTryptophan and brain disorders

Cited by 63

(R)-Ketamine Rapidly Ameliorates the Decreased Spine Density in the Medial Prefrontal Cortex and Hippocampus of Susceptible Mice After Chronic Social Defeat Stress

Zhang, J., Qu, Y., Chang, L., Pu, Y., & Hashimoto, K. (2019) · International Journal of Neuropsychopharmacology

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 55

A prospective comparative study of risperidone long-acting injectable for treatment-resistant schizophrenia with dopamine supersensitivity psychosis

Kimura, H., Kanahara, N., Komatsu, N., Ishige, M., Muneoka, K., Yoshimura, M., Yamanaka, H., Suzuki, T., Komatsu, H., Sasaki, T., et al. (2014) · Schizophrenia Research

Schizophrenia research and treatmentTreatment of Major Depression

Cited by 55

Beneficial effects of (R)-ketamine, but not its metabolite (2R,6R)-hydroxynorketamine, in the depression-like phenotype, inflammatory bone markers, and bone mineral density in a chronic social defeat stress model

Xiong, Z., Fujita, Y., Zhang, K., Pu, Y., Chang, L., Ma, M., Chen, J., & Hashimoto, K. (2019) · Behavioural Brain Research

Treatment of Major DepressionTryptophan and brain disorders

Cited by 49

Role of the mTOR signaling pathway in the rapid antidepressant action of ketamine

Hashimoto, K. (2011) · Expert Review of Neurotherapeutics

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 47

Deficits in auditory P50 inhibition in obsessive-compulsive disorder

Hashimoto, T., Shimizu, E., Koike, K., Orita, Y., Suzuki, T., Kanahara, N., Matsuzawa, D., Fukami, G., Miyatake, R., Shinoda, N., et al. (2008) · Progress in Neuro-Psychopharmacology and Biological Psychiatry

Obsessive-Compulsive Spectrum DisordersPsychoanalysis and Psychopathology Research

Cited by 41

Suppression of abnormal α-synuclein expression by activation of BDNF transcription ameliorates Parkinson’s disease-like pathology

Cao, Q., Luo, S., Yao, W., Qu, Y., Wang, N., Hong, J., Murayama, S., Zhang, Z., Chen, J., Hashimoto, K., et al. (2022) · Molecular Therapy - Nucleic Acids

Parkinson's Disease Mechanisms and TreatmentsNuclear Receptors and Signaling

Cited by 41

Is (S)-norketamine an alternative antidepressant for esketamine?

Hashimoto, K., & Yang, C. (2019) · European Archives of Psychiatry and Clinical Neuroscience

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 37

A novel balanced chromosomal translocation found in subjects with schizophrenia and schizotypal personality disorder: Altered l-serine level associated with disruption of PSAT1 gene expression

Ozeki, Y., Pickard, B. S., Kano, S.-I., Malloy, M. P., Zeledon, M., Sun, D. Q., Fujii, K., Wakui, K., Shirayama, Y., Fukushima, Y., et al. (2011) · Neuroscience Research

Schizophrenia research and treatmentAmino Acid Enzymes and Metabolism

Cited by 34

Intranasal administration of transforming growth factor-β1 elicits rapid-acting antidepressant-like effects in a chronic social defeat stress model: A role of TrkB signaling

Wei, Y., Chang, L., & Hashimoto, K. (2021) · European Neuropsychopharmacology

Treatment of Major DepressionTryptophan and brain disorders

Cited by 30

Small intestinal γδ T17 cells promote SAE through STING/C1q-induced microglial synaptic pruning in male mice

Wu, Y., Zhang, Y., Yu, Y., Wang, X., Zhen, Z., Yuan, Y., Xie, B., Han, M., Wang, M., Zhang, X., et al. (2025) · Nature Communications

Neuroinflammation and Neurodegeneration MechanismsSepsis Diagnosis and Treatment

Cited by 29

Serum Oxytocin, Posttraumatic Coping and C-Reactive Protein in Motor Vehicle Accident Survivors by Gender

Nishi, D., Hashimoto, K., Noguchi, H., Kim, Y., & Matsuoka, Y. (2015) · Neuropsychobiology

Neuroendocrine regulation and behaviorStress Responses and Cortisol

Cited by 23

Gut–microbiota–brain axis in the vulnerability to psychosis in adulthood after repeated cannabis exposure during adolescence

Wan, X., Eguchi, A., Qu, Y., Yang, Y., Chang, L., Shan, J., Mori, C., & Hashimoto, K. (2022) · European Archives of Psychiatry and Clinical Neuroscience

Cannabis and Cannabinoid ResearchGut microbiota and health

Cited by 21

Are NMDA and opioid receptors involved in the antidepressant actions of ketamine?

Hashimoto, K. (2020) · Proceedings of the National Academy of Sciences

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 19

Assessment of a Multi-Assay Biological Diagnostic Test for Mood Disorders in a Japanese Population

Yamamori, H., Ishima, T., Yasuda, Y., Fujimoto, M., Kudo, N., Ohi, K., Hashimoto, K., Takeda, M., & Hashimoto, R. (2016) · Neuroscience Letters

Bipolar Disorder and TreatmentTreatment of Major Depression

Cited by 19

Blood d-serine levels as a predictive biomarker for the rapid antidepressant effects of the NMDA receptor antagonist ketamine

Hashimoto, K. (2014) · Psychopharmacology

Treatment of Major DepressionElectroconvulsive Therapy Studies

Cited by 16

Correction: R-ketamine: a rapid-onset and sustained antidepressant without psychotomimetic side effects

Yang, C., Shirayama, Y., Zhang, J.-C., Ren, Q., Yao, W., Ma, M., Dong, C., & Hashimoto, K. (2020) · Translational Psychiatry

Treatment of Major DepressionTryptophan and brain disorders

Cited by 3