Elling, Ulrich

Single-cell brain organoid screening identifies developmental defects in autism

Li, C., Fleck, J. S., Martins-Costa, C., Burkard, T. R., Themann, J., Stuempflen, M., Peer, A. M., Vertesy, Á., Littleboy, J. B., Esk, C., et al. (2023) · Nature

Pluripotent Stem Cells ResearchGenetics and Neurodevelopmental Disorders

Cited by 283

Murine inner cell mass-derived lineages depend on Sall4 function

Elling, U., Klasen, C., Eisenberger, T., Anlag, K., & Treier, M. (2006) · Proceedings of the National Academy of Sciences

Pluripotent Stem Cells ResearchDevelopmental Biology and Gene Regulation

Cited by 186

A human tissue screen identifies a regulator of ER secretion as a brain-size determinant

Esk, C., Lindenhofer, D., Haendeler, S., Wester, R. A., Pflug, F., Schroeder, B., Bagley, J. A., Elling, U., Zuber, J., von Haeseler, A., et al. (2020) · Science

Neurogenesis and neuroplasticity mechanismsCRISPR and Genetic Engineering

Cited by 170

Multilayered VBC score predicts sgRNAs that efficiently generate loss-of-function alleles

Michlits, G., Jude, J., Hinterndorfer, M., de Almeida, M., Vainorius, G., Hubmann, M., Neumann, T., Schleiffer, A., Burkard, T. R., Fellner, M., et al. (2020) · Nature Methods

CRISPR and Genetic EngineeringRNA Interference and Gene Delivery

Cited by 154

Neutralizing Gatad2a-Chd4-Mbd3/NuRD Complex Facilitates Deterministic Induction of Naive Pluripotency

Mor, N., Rais, Y., Sheban, D., Peles, S., Aguilera-Castrejon, A., Zviran, A., Elinger, D., Viukov, S., Geula, S., Krupalnik, V., et al. (2018) · Cell Stem Cell

Pluripotent Stem Cells ResearchEpigenetics and DNA Methylation

Cited by 79

Canonical PRC1 controls sequence-independent propagation of Polycomb-mediated gene silencing

Moussa, H. F., Bsteh, D., Yelagandula, R., Pribitzer, C., Stecher, K., Bartalska, K., Michetti, L., Wang, J., Zepeda-Martinez, J. A., Elling, U., et al. (2019) · Nature Communications

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 75

Using Functional Genetics in Haploid Cells for Drug Target Identification

Volz, J. C., Schuller, N., & Elling, U. (2019) · Methods in Molecular Biology

CRISPR and Genetic EngineeringCarcinogens and Genotoxicity Assessment

Cited by 4