Crawford, Peter A.

The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease

Youm, Y.-H., Nguyen, K. Y., Grant, R. W., Goldberg, E. L., Bodogai, M., Kim, D., D'Agostino, D., Planavsky, N., Lupfer, C., Kanneganti, T. D., et al. (2015) · Nature Medicine

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 2,172

Lactate metabolism is associated with mammalian mitochondria

Chen, Y.-J., Mahieu, N. G., Huang, X., Singh, M., Crawford, P. A., Johnson, S. L., Gross, R. W., Schaefer, J., & Patti, G. J. (2016) · Nature Chemical Biology

Cancer, Hypoxia, and MetabolismMitochondrial Function and Pathology

Cited by 326

Regulation of myocardial ketone body metabolism by the gut microbiota during nutrient deprivation

Crawford, P. A., Crowley, J. R., Sambandam, N., Muegge, B. D., Costello, E. K., Hamady, M., Knight, R., & Gordon, J. I. (2009) · Proceedings of the National Academy of Sciences

Gut microbiota and healthDiet and metabolism studies

Cited by 278

Activation of Luteinizing Hormone β Gene by Gonadotropin-releasing Hormone Requires the Synergy of Early Growth Response-1 and Steroidogenic Factor-1

Dorn, C., Ou, Q., Svaren, J., Crawford, P. A., & Sadovsky, Y. (1999) · Journal of Biological Chemistry

Hypothalamic control of reproductive hormonesReproductive Biology and Fertility

Cited by 165

X13CMS: Global Tracking of Isotopic Labels in Untargeted Metabolomics

Huang, X., Chen, Y.-J., Cho, K., Nikolskiy, I., Crawford, P. A., & Patti, G. J. (2014) · Analytical Chemistry

Metabolomics and Mass Spectrometry StudiesMicrobial Metabolic Engineering and Bioproduction

Cited by 159

Adrenocortical function and regulation of the steroid 21-hydroxylase gene in NGFI-B-deficient mice

Crawford, P. A., Sadovsky, Y., Woodson, K., Lee, S. L., & Milbrandt, J. (1995) · Molecular and Cellular Biology

Adrenal Hormones and DisordersNuclear Receptors and Signaling

Cited by 145

Ketolysis drives CD8+ T cell effector function through effects on histone acetylation

Luda, K. M., Longo, J., Kitchen-Goosen, S. M., Duimstra, L. R., Ma, E. H., Watson, M. J., Oswald, B. M., Fu, Z., Madaj, Z., Kupai, A., et al. (2023) · Immunity

T-cell and B-cell ImmunologyDiet and metabolism studies

Cited by 140

Hepatocyte-Macrophage Acetoacetate Shuttle Protects Against Tissue Fibrosis

Puchalska, P., Martin, S. E., Huang, X., Lengfeld, J. E., Daniel, B., Graham, M. J., Han, X., Nagy, L., Patti, G. J., & Crawford, P. A. (2019) · Cell Metabolism

Liver physiology and pathologyLiver Disease Diagnosis and Treatment

Cited by 138

Nuclear receptor steroidogenic factor 1 directs embryonic stem cells toward the steroidogenic lineage

Crawford, P. A., Sadovsky, Y., & Milbrandt, J. (1997) · Molecular and Cellular Biology

Pluripotent Stem Cells ResearchEstrogen and related hormone effects

Cited by 134

Isotope Tracing Untargeted Metabolomics Reveals Macrophage Polarization-State-Specific Metabolic Coordination across Intracellular Compartments

Puchalska, P., Huang, X., Martin, S. E., Han, X., Patti, G. J., & Crawford, P. A. (2018) · iScience

Metabolomics and Mass Spectrometry StudiesImmune cells in cancer

Cited by 79

Ketogenesis supports hepatic polyunsaturated fatty acid homeostasis via fatty acid elongation

Queathem, E. D., Moazzami, Z., Stagg, D. B., Nelson, A. B., Fulghum, K., Hayir, A., Seay, A., Gillingham, J. R., d’Avignon, D. A., Han, X., et al. (2025) · Science Advances

Lipid metabolism and biosynthesisDiet and metabolism studies

Cited by 30

APOE4-drives brain bioenergetic shifts independent of Alzheimer’s disease pathology

Lysaker, C. R., Johnson, C. N., Csikos, V., Franczak, E., Benson, M., Gilmore, C. A., Birky, C. J., Davis, X., McCoin, C. S., Smith, K. P., et al. (2026) · npj Dementia

Alzheimer's disease research and treatmentsMitochondrial Function and Pathology

Cited by 1