MacFarlane, Marion

Molecular mechanisms of cell death: recommendations of the nomenclature committee on cell death 2018.

Galluzzi, L., Vitale, I., Aaronson, S. A., Abrams, J. M., Adam, D., Agostinis, P., Alnemri, E. S., Altucci, L., Amelio, I., Andrews, D. W., et al. (2018) · Cell Death & Differentiation

Cell death mechanisms and regulationAutophagy in Disease and Therapy

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A Death Effector Domain Chain DISC Model Reveals a Crucial Role for Caspase-8 Chain Assembly in Mediating Apoptotic Cell Death

Dickens, L. S., Boyd, R. S., Jukes-Jones, R., Hughes, M. A., Robinson, G. L., Fairall, L., Schwabe, J. W. R., Cain, K., & MacFarlane, M. (2012) · Molecular Cell

Cell death mechanisms and regulationCancer-related Molecular Pathways

Cited by 349

Co-operative and Hierarchical Binding of c-FLIP and Caspase-8: A Unified Model Defines How c-FLIP Isoforms Differentially Control Cell Fate

Hughes, M. A., Powley, I. R., Jukes-Jones, R., Horn, S., Feoktistova, M., Fairall, L., Schwabe, J. W. R., Leverkus, M., Cain, K., & MacFarlane, M. (2016) · Molecular Cell

Cell death mechanisms and regulationNF-κB Signaling Pathways

Cited by 257

The ‘complexities’ of life and death: Death receptor signalling platforms

Dickens, L. S., Powley, I. R., Hughes, M. A., & MacFarlane, M. (2012) · Experimental Cell Research

Cell death mechanisms and regulationNF-κB Signaling Pathways

Cited by 208

Caspase-10 Negatively Regulates Caspase-8-Mediated Cell Death, Switching the Response to CD95L in Favor of NF-κB Activation and Cell Survival

Horn, S., Hughes, M. A., Schilling, R., Sticht, C., Tenev, T., Ploesser, M., Meier, P., Sprick, M. R., MacFarlane, M., & Leverkus, M. (2017) · Cell Reports

Cell death mechanisms and regulationNF-κB Signaling Pathways

Cited by 119

Caspase-8 tyrosine-380 phosphorylation inhibits CD95 DISC function by preventing procaspase-8 maturation and cycling within the complex

Powley, I. R., Hughes, M. A., Cain, K., & MacFarlane, M. (2016) · Oncogene

Cell death mechanisms and regulationCancer-related Molecular Pathways

Cited by 54

Asbestos: Modern Insights for Toxicology in the Era of Engineered Nanomaterials

Felley-Bosco, E., & MacFarlane, M. (2018) · Chemical Research in Toxicology

Occupational and environmental lung diseasesCarcinogens and Genotoxicity Assessment

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