Furlong, Eileen E. M.

Transcription factors: from enhancer binding to developmental control

Spitz, F., & Furlong, E. E. M. (2012) · Nature Reviews Genetics

Genomics and Chromatin DynamicsDevelopmental Biology and Gene Regulation

Cited by 2,227

Developmental enhancers and chromosome topology

Furlong, E. E. M., & Levine, M. (2018) · Science

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 641

Enhancer loops appear stable during development and are associated with paused polymerase

Ghavi-Helm, Y., Klein, F. A., Pakozdi, T., Ciglar, L., Noordermeer, D., Huber, W., & Furlong, E. E. M. (2014) · Nature

Genomics and Chromatin DynamicsDevelopmental Biology and Gene Regulation

Cited by 536

Tissue-specific analysis of chromatin state identifies temporal signatures of enhancer activity during embryonic development

Bonn, S., Zinzen, R. P., Girardot, C., Gustafson, E. H., Perez-Gonzalez, A., Delhomme, N., Ghavi-Helm, Y., Wilczyński, B., Riddell, A., & Furlong, E. E. M. (2012) · Nature Genetics

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 502

The cis-regulatory dynamics of embryonic development at single-cell resolution

Cusanovich, D. A., Reddington, J. P., Garfield, D. A., Daza, R. M., Aghamirzaie, D., Marco-Ferreres, R., Pliner, H. A., Christiansen, L., Qiu, X., Steemers, F. J., et al. (2018) · Nature

Genomics and Chromatin DynamicsSingle-cell and spatial transcriptomics

Cited by 363

Highly rearranged chromosomes reveal uncoupling between genome topology and gene expression

Ghavi-Helm, Y., Jankowski, A., Meiers, S., Viales, R. R., Korbel, J. O., & Furlong, E. E. M. (2019) · Nature Genetics

Genomics and Chromatin DynamicsChromosomal and Genetic Variations

Cited by 354

The degree of enhancer or promoter activity is reflected by the levels and directionality of eRNA transcription

Mikhaylichenko, O., Bondarenko, V., Harnett, D., Schor, I. E., Males, M., Viales, R. R., & Furlong, E. E. M. (2018) · Genes & Development

Genomics and Chromatin DynamicsChromosomal and Genetic Variations

Cited by 293

A core transcriptional network for early mesoderm development in Drosophila melanogaster

Sandmann, T., Girardot, C., Brehme, M., Tongprasit, W., Stolc, V., & Furlong, E. E. M. (2007) · Genes & Development

Developmental Biology and Gene RegulationGenomics and Chromatin Dynamics

Cited by 286

A Transcription Factor Collective Defines Cardiac Cell Fate and Reflects Lineage History

Junion, G., Spivakov, M., Girardot, C., Braun, M., Gustafson, E. H., Birney, E., & Furlong, E. E. M. (2012) · Cell

Developmental Biology and Gene RegulationGenomics and Chromatin Dynamics

Cited by 257

The role of transcription in shaping the spatial organization of the genome

van Steensel, B., & Furlong, E. E. M. (2019) · Nature Reviews Molecular Cell Biology

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 247

Shadow Enhancers Are Pervasive Features of Developmental Regulatory Networks

Cannavò, E., Khoueiry, P., Garfield, D. A., Geeleher, P., Zichner, T., Gustafson, E. H., Ciglar, L., Korbel, J. O., & Furlong, E. E. M. (2016) · Current Biology

Genomics and Chromatin DynamicsDevelopmental Biology and Gene Regulation

Cited by 235

Chromatin accessibility profiling methods

Minnoye, L., Marinov, G. K., Krausgruber, T., Pan, L., Marand, A. P., Secchia, S., Greenleaf, W. J., Furlong, E. E. M., Zhao, K., Schmitz, R. J., et al. (2021) · Nature Reviews Methods Primers

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 206

The road ahead in genetics and genomics

McGuire, A. L., Gabriel, S., Tishkoff, S. A., Wonkam, A., Chakravarti, A., Furlong, E. E. M., Treutlein, B., Meissner, A., Chang, H. Y., López-Bigas, N., et al. (2020) · Nature Reviews Genetics

Science, Research, and MedicineGenetic Associations and Epidemiology

Cited by 188

Analysis of variation at transcription factor binding sites in Drosophila and humans

Spivakov, M., Akhtar, J., Kheradpour, P., Beal, K., Girardot, C., Koscielny, G., Herrero, J., Kellis, M., Furlong, E. E., & Birney, E. (2012) · Genome Biology

Genomics and Chromatin DynamicsGenetic Associations and Epidemiology

Cited by 94

Targeted design of synthetic enhancers for selected tissues in the Drosophila embryo

de Almeida, B. P., Schaub, C., Pagani, M., Secchia, S., Furlong, E. E. M., & Stark, A. (2024) · Nature

Genomics and Chromatin DynamicsCRISPR and Genetic Engineering

Cited by 87

Dynamic CRM occupancy reflects a temporal map of developmental progression

Wilczyński, B., & Furlong, E. E. M. (2010) · Molecular Systems Biology

Genomics and Chromatin DynamicsGene Regulatory Network Analysis

Cited by 44

Uncoupling evolutionary changes in DNA sequence, transcription factor occupancy and enhancer activity

Khoueiry, P., Girardot, C., Ciglar, L., Peng, P.-C., Gustafson, E. H., Sinha, S., & Furlong, E. E. (2017) · eLife

Genomics and Chromatin DynamicsDevelopmental Biology and Gene Regulation

Cited by 44