Sethi, Gautam

PI3K/AKT/mTOR signaling transduction pathway and targeted therapies in cancer

Glaviano, A., Foo, A. S. C., Lam, H. Y., Yap, K. C. H., Jacot, W., Jones, R. H., Eng, H., Nair, M. G., Makvandi, P., Geoerger, B., et al. (2023) · Molecular Cancer

PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and Cancer

Cited by 2,138

Inflammation and cancer: how hot is the link?

Aggarwal, B. B., Shishodia, S., Sandur, S. K., Pandey, M. K., & Sethi, G. (2006) · Biochemical Pharmacology

NF-κB Signaling PathwaysInflammatory mediators and NSAID effects

Cited by 1,312

Dual role of autophagy in hallmarks of cancer

Singh, S. S., Vats, S., Chia, A. Y.-Q., Tan, T. Z., Deng, S., Ong, M. S., Arfuso, F., Yap, C. T., Goh, B. C., Sethi, G., et al. (2018) · Oncogene

Autophagy in Disease and TherapyUbiquitin and proteasome pathways

Cited by 542

TNF: A master switch for inflammation to cancer

Sethi, G. (2008) · Frontiers in Bioscience

Immune cells in cancerCytokine Signaling Pathways and Interactions

Cited by 458

The multifaceted role of reactive oxygen species in tumorigenesis

Kirtonia, A., Sethi, G., & Garg, M. (2020) · Cellular and Molecular Life Sciences

Redox biology and oxidative stressCancer and biochemical research

Cited by 452

Resveratrol inhibits proliferation, induces apoptosis, and overcomes chemoresistance through down-regulation of STAT3 and nuclear factor-κB–regulated antiapoptotic and cell survival gene products in human multiple myeloma cells

Bhardwaj, A., Sethi, G., Vadhan-Raj, Bueso-Ramos, C., Takada, Y., Gaur, U., Nair, A. S., Shishodia, S., & Aggarwal, B. B. (2007) · Blood

Multiple Myeloma Research and TreatmentsSirtuins and Resveratrol in Medicine

Cited by 395

NF‐κB as a regulator of cancer metastasis and therapy response: A focus on epithelial–mesenchymal transition

Mirzaei, S., Saghari, S., Bassiri, F., Raesi, R., Zarrabi, A., Hushmandi, K., Sethi, G., & Tergaonkar, V. (2022) · Journal of Cellular Physiology

NF-κB Signaling PathwaysCancer Cells and Metastasis

Cited by 243

Cytoskeletal dynamics in epithelial-mesenchymal transition: insights into therapeutic targets for cancer metastasis

Datta, A., Deng, S., Gopal, V., Yap, K. C.-H., Halim, C. E., Lye, M. L., Ong, M. S., Tan, T. Z., Sethi, G., Hooi, S. C., et al. (2021) · Cancers

Cancer Cells and MetastasisCellular Mechanics and Interactions

Cited by 184

Role of Epigenetics in Inflammation-Associated diseases

Shanmugam, M. K., & Sethi, G. (2013) · Subcellular Biochemistry

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 141

Celastrol in cancer therapy: Recent developments, challenges and prospects

Lim, H. Y., Ong, P. S., Wang, L., Goel, A., Ding, L., Li-Ann Wong, A., Ho, P. C.-L., Sethi, G., Xiang, X., & Goh, B. C. (2021) · Cancer Letters

Natural Compounds in Disease TreatmentNatural product bioactivities and synthesis

Cited by 118

Intricate role of mitochondrial lipid in mitophagy and mitochondrial apoptosis: its implication in cancer therapeutics

Praharaj, P. P., Naik, P. P., Panigrahi, D. P., Bhol, C. S., Mahapatra, K. K., Patra, S., Sethi, G., & Bhutia, S. K. (2019) · Cellular and Molecular Life Sciences

Autophagy in Disease and TherapyCell death mechanisms and regulation

Cited by 104

Neuronal Development-Related miRNAs as Biomarkers for Alzheimer's Disease, Depression, Schizophrenia and Ionizing Radiation Exposure

Segaran, R. C., Chan, L. Y., Wang, H., Sethi, G., & Tang, F. R. (2020) · Current Medicinal Chemistry

MicroRNA in disease regulationAlzheimer's disease research and treatments

Cited by 42

Unveiling the Power of Gut Microbiome in Predicting Neoadjuvant Immunochemotherapy Responses in Esophageal Squamous Cell Carcinoma

Liu, L., Liang, L., Luo, Y., Han, J., Lu, D., Cai, R., Sethi, G., & Mai, S. (2024) · Research

Gut microbiota and healthEsophageal Cancer Research and Treatment

Cited by 22

Blockage of the JAK/STAT3 signaling pathway in multiple myeloma by leelamine

Jung, Y. Y., Um, J.-Y., Nasif, O., Alharbi, S. A., Sethi, G., & Ahn, K. S. (2021) · Phytomedicine

Cytokine Signaling Pathways and InteractionsMultiple Myeloma Research and Treatments

Cited by 19