Leoni, Valerio

NAD+-Dependent Activation of Sirt1 Corrects the Phenotype in a Mouse Model of Mitochondrial Disease

Cerutti, R., Pirinen, E., Lamperti, C., Marchet, S., Sauve, A. A., Li, W., Leoni, V., Schon, E. A., Dantzer, F., Auwerx, J., et al. (2014) · Cell Metabolism

Sirtuins and Resveratrol in MedicineMitochondrial Function and Pathology

Cited by 343

Cholesterol Defect Is Marked across Multiple Rodent Models of Huntington's Disease and Is Manifest in Astrocytes

Valenza, M., Leoni, V., Karasinska, J. M., Petricca, L., Fan, J., Carroll, J., Pouladi, M. A., Fossale, E., Nguyen, H. P., Riess, O., et al. (2010) · The Journal of Neuroscience

Genetic Neurodegenerative DiseasesCholesterol and Lipid Metabolism

Cited by 166

CRISPR/Cas9-mediated knockout of Abcd1 and Abcd2 genes in BV-2 cells: novel microglial models for X-linked Adrenoleukodystrophy

Raas, Q., Gondcaille, C., Hamon, Y., Leoni, V., Caccia, C., Ménétrier, F., Lizard, G., Trompier, D., & Savary, S. (2019) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Metabolism and Genetic DisordersLysosomal Storage Disorders Research

Cited by 53

SREBP2 gene therapy targeting striatal astrocytes ameliorates Huntington’s disease phenotypes

Birolini, G., Verlengia, G., Talpo, F., Maniezzi, C., Zentilin, L., Giacca, M., Conforti, P., Cordiglieri, C., Caccia, C., Leoni, V., et al. (2021) · Brain

Genetic Neurodegenerative DiseasesLysosomal Storage Disorders Research

Cited by 48

On the fluxes of side-chain oxidized oxysterols across blood-brain and blood-CSF barriers and origin of these steroids in CSF (Review)

Björkhem, I., Leoni, V., & Svenningsson, P. (2019) · The Journal of Steroid Biochemistry and Molecular Biology

Cholesterol and Lipid MetabolismBarrier Structure and Function Studies

Cited by 47

Hsp22 Overexpression Induces Myocardial Hypertrophy, Senescence and Reduced Life Span through Enhanced Oxidative Stress

Morin, D., Long, R., Panel, M., Laure, L., Taranu, A., Gueguen, C., Pons, S., Leoni, V., Caccia, C., Vatner, S. F., et al. (2019) · Free Radical Biology and Medicine

Heat shock proteins researchGenetics, Aging, and Longevity in Model Organisms

Cited by 24

ApoE3 vs. ApoE4 Astrocytes: A Detailed Analysis Provides New Insights into Differences in Cholesterol Homeostasis

Staurenghi, E., Leoni, V., Lo Iacono, M., Sottero, B., Testa, G., Giannelli, S., Leonarduzzi, G., & Gamba, P. (2022) · Antioxidants

Cholesterol and Lipid MetabolismAlzheimer's disease research and treatments

Cited by 24

Peroxisomal defects in microglial cells induce a disease-associated microglial signature

Raas, Q., Tawbeh, A., Tahri-Joutey, M., Gondcaille, C., Keime, C., Kaiser, R., Trompier, D., Nasser, B., Leoni, V., Bellanger, E., et al. (2023) · Frontiers in Molecular Neuroscience

Neuroinflammation and Neurodegeneration MechanismsMetabolism and Genetic Disorders

Cited by 16