Rustenhoven, Justin

Functional characterization of the dural sinuses as a neuroimmune interface

Rustenhoven, J., Drieu, A., Mamuladze, T., de Lima, K. A., Dykstra, T., Wall, M., Papadopoulos, Z., Kanamori, M., Salvador, A. F., Baker, W., et al. (2021) · Cell

Neuroinflammation and Neurodegeneration MechanismsMultiple Sclerosis Research Studies

Cited by 685

Skull and vertebral bone marrow are myeloid cell reservoirs for the meninges and CNS parenchyma

Cugurra, A., Mamuladze, T., Rustenhoven, J., Dykstra, T., Beroshvili, G., Greenberg, Z. J., Baker, W., Papadopoulos, Z., Drieu, A., Blackburn, S., et al. (2021) · Science

Neuroinflammation and Neurodegeneration MechanismsMultiple Sclerosis Research Studies

Cited by 681

Meningeal γδ T cells regulate anxiety-like behavior via IL-17a signaling in neurons

Alves de Lima, K., Rustenhoven, J., Da Mesquita, S., Wall, M., Salvador, A. F., Smirnov, I., Martelossi Cebinelli, G., Mamuladze, T., Baker, W., Papadopoulos, Z., et al. (2020) · Nature Immunology

T-cell and B-cell ImmunologyNeuroinflammation and Neurodegeneration Mechanisms

Cited by 416

Brain Pericytes As Mediators of Neuroinflammation

Rustenhoven, J., Jansson, D., Smyth, L. C., & Dragunow, M. (2017) · Trends in Pharmacological Sciences

Neuroinflammation and Neurodegeneration MechanismsBarrier Structure and Function Studies

Cited by 371

Meningeal Immunity and Its Function in Maintenance of the Central Nervous System in Health and Disease

Alves de Lima, K., Rustenhoven, J., & Kipnis, J. (2020) · Annual Review of Immunology

Neuroinflammation and Neurodegeneration MechanismsBacterial Infections and Vaccines

Cited by 348

Parenchymal border macrophages regulate the flow dynamics of the cerebrospinal fluid

Drieu, A., Du, S., Storck, S. E., Rustenhoven, J., Papadopoulos, Z., Dykstra, T., Zhong, F., Kim, K., Blackburn, S., Mamuladze, T., et al. (2022) · Nature

Cerebrospinal fluid and hydrocephalusNeuroinflammation and Neurodegeneration Mechanisms

Cited by 325

Identification of direct connections between the dura and the brain

Smyth, L. C. D., Xu, D., Okar, S. V., Dykstra, T., Rustenhoven, J., Papadopoulos, Z., Bhasiin, K., Kim, M. W., Drieu, A., Mamuladze, T., et al. (2024) · Nature

Cerebrospinal fluid and hydrocephalusBarrier Structure and Function Studies

Cited by 264

Brain borders at the central stage of neuroimmunology

Rustenhoven, J., & Kipnis, J. (2022) · Nature

Neuroinflammation and Neurodegeneration MechanismsBarrier Structure and Function Studies

Cited by 253

TGF-beta1 regulates human brain pericyte inflammatory processes involved in neurovasculature function

Rustenhoven, J., Aalderink, M., Scotter, E. L., Oldfield, R. L., Bergin, P. S., Mee, E. W., Graham, E. S., Faull, R. L. M., Curtis, M. A., Park, T. I.-H., et al. (2016) · Journal of Neuroinflammation

Neuroinflammation and Neurodegeneration MechanismsBarrier Structure and Function Studies

Cited by 201

PU.1 regulates Alzheimer’s disease-associated genes in primary human microglia

Rustenhoven, J., Smith, A. M., Smyth, L. C., Jansson, D., Scotter, E. L., Swanson, M. E. V., Aalderink, M., Coppieters, N., Narayan, P., Handley, R., et al. (2018) · Molecular Neurodegeneration

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 155

Skull bone marrow channels as immune gateways to the central nervous system

Mazzitelli, J. A., Pulous, F. E., Smyth, L. C. D., Kaya, Z., Rustenhoven, J., Moskowitz, M. A., Kipnis, J., & Nahrendorf, M. (2023) · Nature Neuroscience

Neuroinflammation and Neurodegeneration MechanismsBarrier Structure and Function Studies

Cited by 116

Isolation of highly enriched primary human microglia for functional studies

Rustenhoven, J., Park, T. I.-H., Schweder, P., Scotter, J., Correia, J., Smith, A. M., Gibbons, H. M., Oldfield, R. L., Bergin, P. S., Mee, E. W., et al. (2016) · Scientific Reports

Neuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 99

An inducible genetic tool to track and manipulate specific microglial states reveals their plasticity and roles in remyelination

Barclay, K. M., Abduljawad, N., Cheng, Z., Kim, M. W., Zhou, L., Yang, J., Rustenhoven, J., Mazzitelli, J. A., Smyth, L. C. D., Kapadia, D., et al. (2024) · Immunity

Neuroinflammation and Neurodegeneration MechanismsMultiple Sclerosis Research Studies

Cited by 65

Isolation and culture of functional adult human neurons from neurosurgical brain specimens

Park, T. I.-H., Schweder, P., Lee, K., Dieriks, B. V., Jung, Y., Smyth, L., Rustenhoven, J., Mee, E., Heppner, P., Turner, C., et al. (2020) · Brain Communications

Neuroscience and Neuropharmacology ResearchNeural dynamics and brain function

Cited by 28

The amyotrophic lateral sclerosis-linked protein TDP-43 regulates interleukin-6 cytokine production by human brain pericytes

Scotter, E. L., Cao, M. C., Jansson, D., Rustenhoven, J., Smyth, L. C. D., Aalderink, M. C., Siemens, A., Fan, V., Wu, J., Mee, E. W., et al. (2022) · Molecular and Cellular Neuroscience

Amyotrophic Lateral Sclerosis ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 13