Hötzel, Isidro

A strategy for risk mitigation of antibodies with fast clearance

Hötzel, I., Theil, F.-P., Bernstein, L. J., Prabhu, S., Deng, R., Quintana, L., Lutman, J., Sibia, R., Chan, P., Bumbaca, D., et al. (2012) · mAbs

Monoclonal and Polyclonal Antibodies ResearchProtein purification and stability

Cited by 245

Neutral or Detrimental Effects of TREM2 Agonist Antibodies in Preclinical Models of Alzheimer’s Disease and Multiple Sclerosis

Etxeberria, A., Shen, Y.-A. A., Vito, S., Silverman, S. M., Imperio, J., Lalehzadeh, G., Soung, A. L., Du, C., Xie, L., Choy, M. K., et al. (2024) · The Journal of Neuroscience

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 34

In vitro affinity maturation of a natural human antibody overcomes a barrier to in vivo affinity maturation

Li, B., Fouts, A. E., Stengel, K., Luan, P., Dillon, M., Liang, W.-C., Feierbach, B., Kelley, R. F., & Hötzel, I. (2014) · mAbs

Monoclonal and Polyclonal Antibodies ResearchProtein purification and stability

Cited by 28

Deep time structural evolution of retroviral and filoviral surface envelope proteins

Hötzel, I. (2021) · Journal of Virology

HIV Research and TreatmentT-cell and Retrovirus Studies

Cited by 9

Deep-Time Structural Evolution of Retroviral and Filoviral Surface Envelope Proteins

Hötzel, I. (2022) · Journal of Virology

HIV Research and TreatmentT-cell and Retrovirus Studies

Cited by 9

Domain Organization of Lentiviral and Betaretroviral Surface Envelope Glycoproteins Modeled with AlphaFold

Hötzel, I. (2022) · Journal of Virology

HIV Research and TreatmentProtein Structure and Dynamics

Cited by 5