Habener, J F

Glucagon-like peptide 1 (GLP-1)

Müller, T. D., Finan, B., Bloom, S. R., D'Alessio, D., Drucker, D. J., Flatt, P. R., Fritsche, A., Gribble, F., Grill, H. J., Habener, J. F., et al. (2019) · Molecular Metabolism

Diabetes Treatment and ManagementRegulation of Appetite and Obesity

Cited by 1,868

Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats.

Xu, G., Stoffers, D. A., Habener, J. F., & Bonner-Weir, S. (1999) · Diabetes

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 1,209

Glucagon-like peptide I stimulates insulin gene expression and increases cyclic AMP levels in a rat islet cell line.

Drucker, D. J., Philippe, J., Mojsov, S., Chick, W. L., & Habener, J. F. (1987) · Proceedings of the National Academy of Sciences

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 903

Preproglucagon gene expression in pancreas and intestine diversifies at the level of post-translational processing

Mojsov, S., Heinrich, G., Wilson, I. B., Ravazzola, M., Orci, L., & Habener, J. F. (1986) · Journal of Biological Chemistry

Pancreatic function and diabetesNeuropeptides and Animal Physiology

Cited by 724

Discovery, characterization, and clinical development of the glucagon-like peptides

Drucker, D. J., Habener, J. F., & Holst, J. J. (2017) · Journal of Clinical Investigation

Diabetes Treatment and ManagementPancreatic function and diabetes

Cited by 418

Leptin Receptors Expressed on Pancreatic β-Cells

Kieffer, T. J., Heller, R. S., & Habener, J. F. (1996) · Biochemical and Biophysical Research Communications

Pancreatic function and diabetesAdipokines, Inflammation, and Metabolic Diseases

Cited by 326

Pancreatic preproglucagon cDNA contains two glucagon-related coding sequences arranged in tandem

Lund, P. K., Goodman, R. H., Dee, P. C., & Habener, J. F. (1982) · Proceedings of the National Academy of Sciences

Pancreatic function and diabetesNeuropeptides and Animal Physiology

Cited by 295

Insulinotropic Action of Glucagonlike Peptide-I-(7–37) in Diabetic and Nondiabetic Subjects

Nathan, D. M., Schreiber, E., Fogel, H., Mojsov, S., & Habener, J. F. (1992) · Diabetes Care

Diabetes Treatment and ManagementPancreatic function and diabetes

Cited by 289

Leptin Suppression of Insulin Secretion and Gene Expression in Human Pancreatic Islets: Implications for the Development of Adipogenic Diabetes Mellitus1

Seufert, J., Kieffer, T. J., Leech, C. A., Holz, G. G., Moritz, W., Ricordi, C., & Habener, J. F. (1999) · The Journal of Clinical Endocrinology & Metabolism

Pancreatic function and diabetesAdipokines, Inflammation, and Metabolic Diseases

Cited by 278

cAMP-dependent Mobilization of Intracellular Ca2+ Stores by Activation of Ryanodine Receptors in Pancreatic β-Cells

Holz, G. G., Leech, C. A., Heller, R. S., Castonguay, M., & Habener, J. F. (1999) · Journal of Biological Chemistry

Pancreatic function and diabetesIon channel regulation and function

Cited by 220

Glucagon gene sequence. Four of six exons encode separate functional domains of rat pre-proglucagon

Heinrich, G., Gros, P., & Habener, J. F. (1984) · Journal of Biological Chemistry

Pancreatic function and diabetesNeuropeptides and Animal Physiology

Cited by 207

Leptin inhibits insulin gene transcription and reverses hyperinsulinemia in leptin-deficient ob/ob mice

Seufert, J., Kieffer, T. J., & Habener, J. F. (1999) · Proceedings of the National Academy of Sciences

Pancreatic function and diabetesAdipokines, Inflammation, and Metabolic Diseases

Cited by 193

Activation of a cAMP-regulated Ca2+-Signaling Pathway in Pancreatic β-Cells by the Insulinotropic Hormone Glucagon-like Peptide-1

Holz, G. G., Leech, C. A., & Habener, J. F. (1995) · Journal of Biological Chemistry

Pancreatic function and diabetesIon channel regulation and function

Cited by 188

Insulinotropic Glucagon-Like Peptide I Receptor Expression in Glucagon-Producing α-Cells of the Rat Endocrine Pancreas

Heller, R. S., Kieffer, T. J., & Habener, J. F. (1997) · Diabetes

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 179

Pre-proglucagon messenger ribonucleic acid: nucleotide and encoded amino acid sequences of the rat pancreatic complementary deoxyribonucleic acid

HEINRICH, G., GROS, P., LUND, P. K., BENTLEY, R. C., & HABENER, J. F. (1984) · Endocrinology

Pancreatic function and diabetesNeuropeptides and Animal Physiology

Cited by 158

Anglerfish islet pre-proglucagon II. Nucleotide and corresponding amino acid sequence of the cDNA

Lund, P. K., Goodman, R. H., Montminy, M. R., Dee, P. C., & Habener, J. F. (1983) · Journal of Biological Chemistry

Pancreatic function and diabetesNeuropeptides and Animal Physiology

Cited by 146

Inhibition of Cyclin-dependent Kinase 5 Activity Protects Pancreatic Beta Cells from Glucotoxicity

Ubeda, M., Rukstalis, J. M., & Habener, J. F. (2006) · Journal of Biological Chemistry

Pancreatic function and diabetesEndoplasmic Reticulum Stress and Disease

Cited by 138

Identification and functional characterization of melatonin Mel 1a receptors in pancreatic β cells: potential role in incretin-mediated cell function by sensitization of cAMP signaling

Kemp, D. M., Ubeda, M., & Habener, J. F. (2002) · Molecular and Cellular Endocrinology

Pancreatic function and diabetesCircadian rhythm and melatonin

Cited by 122

Pancreatic pre-proglucagons are encoded by two separate mRNAs

Lund, P. K., Goodman, R. H., & Habener, J. F. (1981) · Journal of Biological Chemistry

Pancreatic function and diabetesNeuropeptides and Animal Physiology

Cited by 70

Glucagon stimulates expression of the inducible cAMP early repressor and suppresses insulin gene expression in pancreatic beta-cells.

Hussain, M. A., Daniel, P. B., & Habener, J. F. (2000) · Diabetes

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 40