Ioannou, Maria S.

Neuron-Astrocyte Metabolic Coupling Protects against Activity-Induced Fatty Acid Toxicity

Ioannou, M. S., Jackson, J., Sheu, S.-H., Chang, C.-L., Weigel, A. V., Liu, H., Pasolli, H. A., Xu, C. S., Pang, S., Matthies, D., et al. (2019) · Cell

Lipid metabolism and biosynthesisNeuroscience and Neuropharmacology Research

Cited by 760

Lipid droplets in the nervous system

Ralhan, I., Chang, C.-L., Lippincott-Schwartz, J., & Ioannou, M. S. (2021) · Journal of Cell Biology

Lipid metabolism and biosynthesisCancer, Lipids, and Metabolism

Cited by 281

Spastin tethers lipid droplets to peroxisomes and directs fatty acid trafficking through ESCRT-III

Chang, C.-L., Weigel, A. V., Ioannou, M. S., Pasolli, H. A., Xu, C. S., Peale, D. R., Shtengel, G., Freeman, M., Hess, H. F., Blackstone, C., et al. (2019) · Journal of Cell Biology

Lipid metabolism and biosynthesisCellular transport and secretion

Cited by 206

Neuronal ROS-Induced Glial Lipid Droplet Formation is Altered by Loss of Alzheimer's Disease-Associated Genes

Moulton, M. J., Barish, S., Ralhan, I., Chang, J., Goodman, L. D., Harland, J. G., Marcogliese, P. C., Johansson, J. O., Ioannou, M. S., & Bellen, H. J. (2021) · Proceedings of the National Academy of Sciences

Alzheimer's disease research and treatmentsLipid metabolism and biosynthesis

Cited by 180

Protective ApoE variants support neuronal function by effluxing oxidized phospholipids

Ralhan, I., Do, A. D., Bae, J.-Y., Feringa, F. M., Cai, W., Chang, J., Chik, K., Lee, N. Y. J., Gerry, C. J., van der Kant, R., et al. (2026) · Neuron

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 23

DENND2B activates Rab35 at the intercellular bridge, regulating cytokinetic abscission and tetraploidy

Kumar, R., Francis, V., Ioannou, M. S., Aguila, A., Khan, M., Banks, E., Kulasekaran, G., & McPherson, P. S. (2023) · Cell Reports

Microtubule and mitosis dynamicsCellular transport and secretion

Cited by 13

DENND2B activates Rab35 at the intercellular bridge regulating cytokinetic abscission and tetraploidy

Kumar, R., Francis, V., Ioannou, M. S., Aguila, A., Banks, E., Kulasekaran, G., Khan, M., & McPherson, P. S. (2023) · Cell Reports

Microtubule and mitosis dynamicsCellular transport and secretion

Cited by 13

Protective ApoE variants support neuronal function by extracting peroxidated lipids

Ralhan, I., Do, A. D., Bae, J.-Y., Feringa, F. M., Cai, W., Chang, J., Chik, K., Lee, N. Y., Gerry, C., van der Kant, R., et al. (2025) · bioRxiv

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 4

ApoE4 impairs astrocyte lipid droplet formation via endolysosomal dysfunction

Ralhan, I., Bae, J.-Y., Lee, N. Y., Cai, W., Chang, J., Jarad, S., Gu, H., Zhang, D., & Ioannou, M. S. (2026) · bioRxiv (Cold Spring Harbor Laboratory)

Alzheimer's disease research and treatmentsLipid metabolism and biosynthesis

Cited by 0