Borthwick, Lee A.

T H 2 and T H 17 inflammatory pathways are reciprocally regulated in asthma

Choy, D. F., Hart, K. M., Borthwick, L. A., Shikotra, A., Nagarkar, D. R., Siddiqui, S., Jia, G., Ohri, C. M., Doran, E., Vannella, K. M., et al. (2015) · Science Translational Medicine

Asthma and respiratory diseasesIL-33, ST2, and ILC Pathways

Cited by 450

Cytokine mediated tissue fibrosis

Borthwick, L. A., Wynn, T. A., & Fisher, A. J. (2013) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Wound Healing and TreatmentsLiver physiology and pathology

Cited by 375

Identification of a broadly fibrogenic macrophage subset induced by type 3 inflammation

Fabre, T., Barron, A. M. S., Christensen, S. M., Asano, S., Bound, K., Lech, M. P., Wadsworth, M. H., Chen, X., Wang, C., Wang, J., et al. (2023) · Science Immunology

Liver physiology and pathologyCardiac Fibrosis and Remodeling

Cited by 355

The IL-1 cytokine family and its role in inflammation and fibrosis in the lung

Borthwick, L. A. (2016) · Seminars in Immunopathology

Cytokine Signaling Pathways and InteractionsInterstitial Lung Diseases and Idiopathic Pulmonary Fibrosis

Cited by 294

Combinatorial targeting of TSLP, IL-25, and IL-33 in type 2 cytokine–driven inflammation and fibrosis

Vannella, K. M., Ramalingam, T. R., Borthwick, L. A., Barron, L., Hart, K. M., Thompson, R. W., Kindrachuk, K. N., Cheever, A. W., White, S., Budelsky, A. L., et al. (2016) · Science Translational Medicine

IL-33, ST2, and ILC PathwaysAsthma and respiratory diseases

Cited by 188

Type 2 immunity is protective in metabolic disease but exacerbates NAFLD collaboratively with TGF-β

Hart, K. M., Fabre, T., Sciurba, J. C., Gieseck, R. L., Borthwick, L. A., Vannella, K. M., Acciani, T. H., de Queiroz Prado, R., Thompson, R. W., White, S., et al. (2017) · Science Translational Medicine

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 143

Macrophages are critical to the maintenance of IL-13-dependent lung inflammation and fibrosis

Borthwick, L. A., Barron, L., Hart, K. M., Vannella, K. M., Thompson, R. W., Oland, S., Cheever, A., Sciurba, J., Ramalingam, T. R., Fisher, A. J., et al. (2016) · Mucosal Immunology

Asthma and respiratory diseasesImmune cells in cancer

Cited by 138

Translational pharmacology of an inhaled small molecule αvβ6 integrin inhibitor for idiopathic pulmonary fibrosis

John, A. E., Graves, R. H., Pun, K. T., Vitulli, G., Forty, E. J., Mercer, P. F., Morrell, J. L., Barrett, J. W., Rogers, R. F., Hafeji, M., et al. (2020) · Nature Communications

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisCell Adhesion Molecules Research

Cited by 131

A Bioreactor Technology for Modeling Fibrosis in Human and Rodent Precision‐Cut Liver Slices

Paish, H. L., Reed, L. H., Brown, H., Bryan, M. C., Govaere, O., Leslie, J., Barksby, B. S., Garcia Macia, M., Watson, A., Xu, X., et al. (2019) · Hepatology

Liver physiology and pathologyLiver Disease Diagnosis and Treatment

Cited by 106

Anti-Cholestatic Therapy with Obeticholic Acid Improves Short-Term Memory in Bile Duct-Ligated Mice

Gee, L. M. V., Barron-Millar, B., Leslie, J., Richardson, C., Zaki, M. Y. W., Luli, S., Burgoyne, R. A., Cameron, R. I. T., Smith, G. R., Brain, J. G., et al. (2023) · The American Journal of Pathology

Liver Diseases and ImmunityDrug Transport and Resistance Mechanisms

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