Long, Jonathan Z.

A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

Boström, P., Wu, J., Jedrychowski, M. P., Korde, A., Ye, L., Lo, J. C., Rasbach, K. A., Boström, E. A., Choi, J. H., Long, J. Z., et al. (2012) · Nature

Adipose Tissue and MetabolismAdipokines, Inflammation, and Metabolic Diseases

Cited by 4,810

Monoacylglycerol lipase regulates a fatty acid network that promotes cancer pathogenesis

Nomura, D. K., Long, J. Z., Niessen, S., Hoover, H. S., Ng, S.-W., & Cravatt, B. F. (2010) · Cell

Cancer, Lipids, and MetabolismLipid metabolism and biosynthesis

Cited by 1,002

Meteorin-like is a hormone that regulates immune-adipose interactions to increase beige fat thermogenesis

Rao, R. R., Long, J. Z., White, J. P., Svensson, K. J., Lou, J., Lokurkar, I., Jedrychowski, M. P., Ruas, J. L., Wrann, C. D., Lo, J. C., et al. (2014) · Cell

Adipose Tissue and MetabolismAdipokines, Inflammation, and Metabolic Diseases

Cited by 973

Endocannabinoid Hydrolysis Generates Brain Prostaglandins That Promote Neuroinflammation

Nomura, D. K., Morrison, B. E., Blankman, J. L., Long, J. Z., Kinsey, S. G., Marcondes, M. C. G., Ward, A. M., Hahn, Y. K., Lichtman, A. H., Conti, B., et al. (2011) · Science

Cannabis and Cannabinoid ResearchInflammatory mediators and NSAID effects

Cited by 727

Chronic monoacylglycerol lipase blockade causes functional antagonism of the endocannabinoid system

Schlosburg, J. E., Blankman, J. L., Long, J. Z., Nomura, D. K., Pan, B., Kinsey, S. G., Nguyen, P. T., Ramesh, D., Booker, L., Burston, J. J., et al. (2010) · Nature Neuroscience

Cannabis and Cannabinoid ResearchPain Mechanisms and Treatments

Cited by 641

Discovery and Characterization of a Highly Selective FAAH Inhibitor that Reduces Inflammatory Pain

Ahn, K., Johnson, D. S., Mileni, M., Beidler, D., Long, J. Z., McKinney, M. K., Weerapana, E., Sadagopan, N., Liimatta, M., Smith, S. E., et al. (2009) · Chemistry & Biology

Cannabis and Cannabinoid ResearchEicosanoids and Hypertension Pharmacology

Cited by 439

An exercise-inducible metabolite that suppresses feeding and obesity

Li, V. L., He, Y., Contrepois, K., Liu, H., Kim, J. T., Wiggenhorn, A. L., Tanzo, J. T., Tung, A. S.-H., Lyu, X., Zushin, P.-J. H., et al. (2022) · Nature

Regulation of Appetite and ObesityAdipokines, Inflammation, and Metabolic Diseases

Cited by 331

Blockade of Endocannabinoid-Degrading Enzymes Attenuates Neuropathic Pain

Kinsey, S. G., Long, J. Z., O’Neal, S. T., Abdullah, R. A., Poklis, J. L., Boger, D. L., Cravatt, B. F., & Lichtman, A. H. (2009) · The Journal of Pharmacology and Experimental Therapeutics

Cannabis and Cannabinoid ResearchPain Mechanisms and Treatments

Cited by 330

The Secreted Enzyme PM20D1 Regulates Lipidated Amino Acid Uncouplers of Mitochondria

Long, J. Z., Svensson, K. J., Bateman, L. A., Lin, H., Kamenecka, T., Lokurkar, I. A., Lou, J., Rao, R. R., Chang, M. R., Jedrychowski, M. P., et al. (2016) · Cell

Adipose Tissue and MetabolismLipid metabolism and biosynthesis

Cited by 257

Inhibition of endocannabinoid catabolic enzymes elicits anxiolytic-like effects in the marble burying assay

Kinsey, S. G., O'Neal, S. T., Long, J. Z., Cravatt, B. F., & Lichtman, A. H. (2011) · Pharmacology Biochemistry and Behavior

Cannabis and Cannabinoid ResearchMedicinal Plant Extracts Effects

Cited by 170

Fatty Acid Amide Hydrolase and Monoacylglycerol Lipase Inhibitors Produce Anti-Allodynic Effects in Mice Through Distinct Cannabinoid Receptor Mechanisms

Kinsey, S. G., Long, J. Z., Cravatt, B. F., & Lichtman, A. H. (2010) · The Journal of Pain

Cannabis and Cannabinoid ResearchPain Mechanisms and Treatments

Cited by 118

The fatty acid amide hydrolase (FAAH) inhibitor PF‐3845 acts in the nervous system to reverse LPS‐induced tactile allodynia in mice

Booker, L., Kinsey, S. G., Abdullah, R. A., Blankman, J. L., Long, J. Z., Ezzili, C., Boger, D. L., Cravatt, B. F., & Lichtman, A. H. (2012) · British Journal of Pharmacology

Cannabis and Cannabinoid ResearchPain Mechanisms and Treatments

Cited by 116

Blockade of 2-arachidonoylglycerol hydrolysis produces antidepressant-like effects and enhances adult hippocampal neurogenesis and synaptic plasticity

Zhang, Z., Wang, W., Zhong, P., Liu, S. J., Long, J. Z., Zhao, L., Gao, H., Cravatt, B. F., & Liu, Q. (2015) · Hippocampus

Cannabis and Cannabinoid ResearchNeurogenesis and neuroplasticity mechanisms

Cited by 89

Prolonged monoacylglycerol lipase blockade causes equivalent cannabinoid receptor type 1 receptor-mediated adaptations in fatty acid amide hydrolase wild-type and knockout mice

Schlosburg, J. E., Kinsey, S. G., Ignatowska-Jankowska, B., Ramesh, D., Abdullah, R. A., Tao, Q., Booker, L., Long, J. Z., Selley, D. E., Cravatt, B. F., et al. (2014) · The Journal of Pharmacology and Experimental Therapeutics

Cannabis and Cannabinoid ResearchPain Mechanisms and Treatments

Cited by 44

Binding and sequestration of poison frog alkaloids by a plasma globulin

Alvarez-Buylla, A., Fischer, M.-T., Moya Garzon, M. D., Rangel, A. E., Tapia, E. E., Tanzo, J. T., Soh, H. T., Coloma, L. A., Long, J. Z., & O'Connell, L. A. (2023) · eLife

Venomous Animal Envenomation and StudiesProtein Interaction Studies and Fluorescence Analysis

Cited by 32

A small molecule PTER-selective inhibitor reduces food intake and body weight

Fu, S., Wang, L., Li, V. L., Lyu, X., Wei, W., Shi, X., Deng, S., Barber, J. L., Tahir, U. A., Adams, C., et al. (2026) · Cell Chemical Biology

Regulation of Appetite and ObesityPharmacology and Obesity Treatment

Cited by 2

A small molecule PTER-selective inhibitor reduces food intake and body weight

Fu, S., Wang, L., Li, V. L., Lyu, X., Wei, W., Shi, X., Deng, S., Barber, J. L., Tahir, U. A., Adams, C., et al. (2026) · Cell chemical biology

Regulation of Appetite and ObesityPharmacology and Obesity Treatment

Cited by 2