Griffith, Malachi

The clonal and mutational evolution spectrum of primary triple-negative breast cancers

Shah, S. P., Roth, A., Goya, R., Oloumi, A., Ha, G., Zhao, Y., Turashvili, G., Ding, J., Tse, K., Haffari, G., et al. (2012) · Nature

Cancer Genomics and DiagnosticsBreast Cancer Treatment Studies

Cited by 1,967

Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma

Morin, R. D., Mendez-Lago, M., Mungall, A. J., Goya, R., Mungall, K. L., Corbett, R. D., Johnson, N. A., Severson, T. M., Chiu, R., Field, M., et al. (2011) · Nature

Lymphoma Diagnosis and TreatmentGenomics and Chromatin Dynamics

Cited by 1,614

Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells

Morin, R. D., O’Connor, M. D., Griffith, M., Kuchenbauer, F., Delaney, A., Prabhu, A.-L., Zhao, Y., McDonald, H., Zeng, T., Hirst, M., et al. (2008) · Genome Research

MicroRNA in disease regulationGenomics and Phylogenetic Studies

Cited by 1,110

CIViC is a community knowledgebase for expert crowdsourcing the clinical interpretation of variants in cancer

Griffith, M., Spies, N. C., Krysiak, K., McMichael, J. F., Coffman, A. C., Danos, A. M., Ainscough, B. J., Ramirez, C. A., Rieke, D. T., Kujan, L., et al. (2017) · Nature Genetics

Genomics and Rare DiseasesCancer Genomics and Diagnostics

Cited by 628

Convergent loss of PTEN leads to clinical resistance to a PI(3)Kα inhibitor

Juric, D., Castel, P., Griffith, M., Griffith, O. L., Won, H. H., Ellis, H., Ebbesen, S. H., Ainscough, B. J., Ramu, A., Iyer, G., et al. (2015) · Nature

PI3K/AKT/mTOR signaling in cancerCancer Genomics and Diagnostics

Cited by 588

deFuse: An Algorithm for Gene Fusion Discovery in Tumor RNA-Seq Data

McPherson, A., Hormozdiari, F., Zayed, A., Giuliany, R., Ha, G., Sun, M. G. F., Griffith, M., Heravi Moussavi, A., Senz, J., Melnyk, N., et al. (2011) · PLoS Computational Biology

Cancer Genomics and DiagnosticsGenomics and Phylogenetic Studies

Cited by 557

Mutant U2AF1 Expression Alters Hematopoiesis and Pre-mRNA Splicing In Vivo

Shirai, C. L., Ley, J. N., White, B. S., Kim, S., Tibbitts, J., Shao, J., Ndonwi, M., Wadugu, B., Duncavage, E. J., Okeyo-Owuor, T., et al. (2015) · Cancer Cell

RNA Research and SplicingAcute Myeloid Leukemia Research

Cited by 287

Analysis of the prostate cancer cell line LNCaP transcriptome using a sequencing-by-synthesis approach

Bainbridge, M. N., Warren, R. L., Hirst, M., Romanuik, T., Zeng, T., Go, A., Delaney, A., Griffith, M., Hickenbotham, M., Magrini, V., et al. (2006) · BMC Genomics

Genomics and Phylogenetic StudiesGene expression and cancer classification

Cited by 222

ORegAnno 3.0: a community-driven resource for curated regulatory annotation

Lesurf, R., Cotto, K. C., Wang, G., Griffith, M., Kasaian, K., Jones, S. J. M., Montgomery, S. B., Griffith, O. L., & The Open Regulatory Annotation Consortium (2016) · Nucleic Acids Research

Genomics and Chromatin DynamicsGenomics and Phylogenetic Studies

Cited by 201

A harmonized meta-knowledgebase of clinical interpretations of somatic genomic variants in cancer

Variant Interpretation for Cancer Consortium, Wagner, A. H., Walsh, B., Mayfield, G., Tamborero, D., Sonkin, D., Krysiak, K., Deu-Pons, J., Duren, R. P., Gao, J., et al. (2020) · Nature Genetics

Genomics and Rare DiseasesCancer Genomics and Diagnostics

Cited by 164

Interaction of Cyclin-Dependent Kinase 12/CrkRS with Cyclin K1 Is Required for the Phosphorylation of the C-Terminal Domain of RNA Polymerase II

Cheng, S.-W. G., Kuzyk, M. A., Moradian, A., Ichu, T.-A., Chang, V. C.-D., Tien, J. F., Vollett, S. E., Griffith, M., Marra, M. A., & Morin, G. B. (2012) · Molecular and Cellular Biology

Genomics and Chromatin DynamicsRNA Research and Splicing

Cited by 124

Hippo Signaling Influences HNF4A and FOXA2 Enhancer Switching during Hepatocyte Differentiation

Alder, O., Cullum, R., Lee, S., Kan, A. C., Wei, W., Yi, Y., Garside, V. C., Bilenky, M., Griffith, M., Morrissy, A. S., et al. (2014) · Cell Reports

Hippo pathway signaling and YAP/TAZGenomics and Chromatin Dynamics

Cited by 113

Yap1 Mediates Trametinib Resistance in Head and Neck Squamous Cell Carcinomas

Mudianto, T., Campbell, K. M., Webb, J., Zolkind, P., Skidmore, Z. L., Riley, R., Barnell, E. K., Ozgenc, I., Giri, T., Dunn, G. P., et al. (2021) · Clinical Cancer Research

Hippo pathway signaling and YAP/TAZMelanoma and MAPK Pathways

Cited by 33