Osorio, Fernando G.

Splicing-directed therapy in a new mouse model of human accelerated aging

Osorio, F. G., Navarro, C. L., Cadiñanos, J., López-Mejía, I. C., Quirós, P. M., Bartoli, C., Rivera, J., Tazi, J., Guzmán, G., Varela, I., et al. (2011) · Science Translational Medicine

Nuclear Structure and FunctionRNA Research and Splicing

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Nuclear lamina defects cause ATM-dependent NF-κB activation and link accelerated aging to a systemic inflammatory response

Osorio, F. G., Bárcena, C., Soria-Valles, C., Ramsay, A. J., de Carlos, F., Cobo, J., Fueyo, A., Freije, J. M. P., & López-Otín, C. (2012) · Genes & Development

Nuclear Structure and FunctionGenetics, Aging, and Longevity in Model Organisms

Cited by 276

Loss of MT1-MMP causes cell senescence and nuclear defects which can be reversed by retinoic acid

Gutiérrez‐Fernández, A., Soria‐Valles, C., Osorio, F. G., Gutiérrez‐Abril, J., Garabaya, C., Aguirre, A., Fueyo, A., Fernández‐García, M. S., Puente, X. S., & López‐Otín, C. (2015) · The EMBO Journal

Telomeres, Telomerase, and SenescenceNuclear Structure and Function

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