Bracher, Andreas

Selective inhibitors of the FK506-binding protein 51 by induced fit

Gaali, S., Kirschner, A., Cuboni, S., Hartmann, J., Kozany, C., Balsevich, G., Namendorf, C., Fernandez-Vizarra, P., Sippel, C., Zannas, A. S., et al. (2015) · Nature Chemical Biology

Signaling Pathways in DiseaseTreatment of Major Depression

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Firefly luciferase mutants as sensors of proteome stress

Gupta, R., Kasturi, P., Bracher, A., Loew, C., Zheng, M., Villella, A., Garza, D., Hartl, F. U., & Raychaudhuri, S. (2011) · Nature Methods

Heat shock proteins researchGenetics, Aging, and Longevity in Model Organisms

Cited by 219

Structure and function of the AAA+ protein CbbX, a red-type Rubisco activase

Mueller-Cajar, O., Stotz, M., Wendler, P., Hartl, F. U., Bracher, A., & Hayer-Hartl, M. (2011) · Nature

Photosynthetic Processes and MechanismsEnzyme Structure and Function

Cited by 190

Large FK506-binding proteins shape the pharmacology of rapamycin

März, A. M., Fabian, A.-K., Kozany, C., Bracher, A., & Hausch, F. (2013) · Molecular and Cellular Biology

PI3K/AKT/mTOR signaling in cancerSignaling Pathways in Disease

Cited by 141

Evaluation of synthetic FK506 analogues as ligands for the FK506-binding proteins 51 and 52

Gopalakrishnan, R., Kozany, C., Gaali, S., Kress, C., Hoogeland, B., Bracher, A., & Hausch, F. (2012) · Journal of Medicinal Chemistry

Signaling Pathways in DiseasePI3K/AKT/mTOR signaling in cancer

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Structural characterization of the PPIase domain of FKBP51, a cochaperone of human Hsp90

Bracher, A., Kozany, C., Thost, A.-K., & Hausch, F. (2011) · Acta Crystallographica Section D Biological Crystallography

Signaling Pathways in DiseaseHeat shock proteins research

Cited by 62

Increasing the efficiency of ligands for FK506-binding protein 51 by conformational control

Wang, Y., Kirschner, A., Fabian, A.-K., Gopalakrishnan, R., Kress, C., Hoogeland, B., Koch, U., Kozany, C., Bracher, A., & Hausch, F. (2013) · Journal of Medicinal Chemistry

Signaling Pathways in DiseaseChemical Synthesis and Analysis

Cited by 60

Crystal Structure of an Archaeal Actin Homolog

Roeben, A., Kofler, C., Nagy, I., Nickell, S., Ulrich Hartl, F., & Bracher, A. (2006) · Journal of Molecular Biology

Protein Structure and DynamicsEnzyme Structure and Function

Cited by 53

Exploration of pipecolate sulfonamides as binders of the FK506-binding proteins 51 and 52

Gopalakrishnan, R., Kozany, C., Wang, Y., Schneider, S., Hoogeland, B., Bracher, A., & Hausch, F. (2012) · Journal of Medicinal Chemistry

Chemical Synthesis and AnalysisSignaling Pathways in Disease

Cited by 52

Crystal structures of the free and ligand-bound FK1–FK2 domain segment of FKBP52 reveal a flexible inter-domain hinge

Bracher, A., Kozany, C., Hähle, A., Wild, P., Zacharias, M., & Hausch, F. (2013) · Journal of Molecular Biology

Signaling Pathways in DiseaseHeat shock proteins research

Cited by 45

Structural analyses define the molecular basis of clusterin chaperone function

Yuste-Checa, P., Carvajal, A. I., Mi, C., Paatz, S., Hartl, F. U., & Bracher, A. (2025) · Nature Structural & Molecular Biology

Clusterin in disease pathologyHeat shock proteins research

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