Porse, Bo T.

Transcriptional Heterogeneity and Lineage Commitment in Myeloid Progenitors

Paul, F., Arkin, Y., Giladi, A., Jaitin, D. A., Kenigsberg, E., Keren-Shaul, H., Winter, D., Lara-Astiaso, D., Gury, M., Weiner, A., et al. (2015) · Cell

Single-cell and spatial transcriptomicsHematopoietic Stem Cell Transplantation

Cited by 1,082

The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells

Bracken, A. P., Kleine-Kohlbrecher, D., Dietrich, N., Pasini, D., Gargiulo, G., Beekman, C., Theilgaard-Mönch, K., Minucci, S., Porse, B. T., Marine, J.-C., et al. (2007) · Genes & Development

Epigenetics and DNA MethylationTelomeres, Telomerase, and Senescence

Cited by 850

EZH2 is a potential therapeutic target for H3K27M-mutant pediatric gliomas

Mohammad, F., Weissmann, S., Leblanc, B., Pandey, D. P., Højfeldt, J. W., Comet, I., Zheng, C., Johansen, J. V., Rapin, N., Porse, B. T., et al. (2017) · Nature Medicine

Glioma Diagnosis and TreatmentChromatin Remodeling and Cancer

Cited by 535

NMD is essential for hematopoietic stem and progenitor cells and for eliminating by-products of programmed DNA rearrangements

Weischenfeldt, J., Damgaard, I., Bryder, D., Theilgaard-Mönch, K., Thoren, L. A., Nielsen, F. C., Jacobsen, S. E. W., Nerlov, C., & Porse, B. T. (2008) · Genes & Development

RNA Research and SplicingHematopoietic Stem Cell Transplantation

Cited by 288

Loss of TET2 in hematopoietic cells leads to DNA hypermethylation of active enhancers and induction of leukemogenesis

Rasmussen, K. D., Jia, G., Johansen, J. V., Pedersen, M. T., Rapin, N., Bagger, F. O., Porse, B. T., Bernard, O. A., Christensen, J., & Helin, K. (2015) · Genes & Development

Acute Myeloid Leukemia ResearchEpigenetics and DNA Methylation

Cited by 270

PSD-95 is post-transcriptionally repressed during early neural development by PTBP1 and PTBP2

Zheng, S., Gray, E. E., Chawla, G., Porse, B. T., O'Dell, T. J., & Black, D. L. (2012) · Nature Neuroscience

RNA Research and SplicingNeuroscience and Neuropharmacology Research

Cited by 254

Modeling of C/EBPα Mutant Acute Myeloid Leukemia Reveals a Common Expression Signature of Committed Myeloid Leukemia-Initiating Cells

Kirstetter, P., Schuster, M. B., Bereshchenko, O., Moore, S., Dvinge, H., Kurz, E., Theilgaard-Mönch, K., Månsson, R., Pedersen, T. Å., Pabst, T., et al. (2008) · Cancer Cell

Acute Myeloid Leukemia ResearchRetinoids in leukemia and cellular processes

Cited by 251

Loss of C/EBPα cell cycle control increases myeloid progenitor proliferation and transforms the neutrophil granulocyte lineage

Porse, B. T., Bryder, D., Theilgaard-Mönch, K., Hasemann, M. S., Anderson, K., Damgaard, I., Jacobsen, S. E. W., & Nerlov, C. (2005) · The Journal of Experimental Medicine

Acute Myeloid Leukemia ResearchRetinoids in leukemia and cellular processes

Cited by 117

Lipocalin 2 is protective against E. coli pneumonia

Wu, H., Santoni-Rugiu, E., Ralfkiaer, E., Porse, B. T., Moser, C., Høiby, N., Borregaard, N., & Cowland, J. B. (2010) · Respiratory Research

Immune Response and InflammationAntimicrobial Peptides and Activities

Cited by 82

Enhancer and transcription factor dynamics during myeloid differentiation reveal an early differentiation block in Cebpa null progenitors

Pundhir, S., Bratt Lauridsen, F. K., Schuster, M. B., Jakobsen, J. S., Ge, Y., Schoof, E. M., Rapin, N., Waage, J., Hasemann, M. S., & Porse, B. T. (2018) · Cell Reports

Genomics and Chromatin DynamicsHematopoietic Stem Cell Transplantation

Cited by 77