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CEBPA mutations in acute myeloid leukemia: implications in risk stratification and treatment

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Histone methyltransferase SETDB1 safeguards mouse fetal hematopoiesis by suppressing activation of cryptic enhancers

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Establishment of a chemokine-based prognostic model and identification of CXCL10+ M1 macrophages as predictors of neoadjuvant therapy efficacy in colorectal cancer

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Nemo‐like kinase blocks myeloid differentiation by targeting tumor suppressor C/ EBPα in AML

Singh, A. K., Thacker, G., Upadhyay, V., Mishra, M., Sharma, A., Sethi, A., Chowdhury, S., Siddiqui, S. I., Verma, S. P., Pandey, A., et al. (2024) · FEBS Journal · doi:10.1111/febs.17245 · Cited by 5 · see citing works

PPARγ accelerates OSCC progression via Th17 polarization and CEBPA/IL-17C signaling

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Non-coding variants impact cis-regulatory coordination in a cell type-specific manner

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In vivo temporal resolution of acute promyelocytic leukemia progression reveals a role of Klf4 in suppressing early leukemic transformationPreprint

Martín, G. M., Santoro, F., Blanco, E., Figueroa, G. P. G., Dily, F. L., Frigè, G., Vidal, E., Mugianesi, F., Ballaré, C., Gutiérrez, A., et al. (2022) · Genes & Development · doi:10.1101/gad.349115.121 · Cited by 5 · see citing works

Intrinsic changes in cell differentiation and identity drive impaired wound healing in aged female murine skin

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Tumor-associated macrophages: orchestrators of the tumor microenvironment

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Discrimination of distinct chicken M cell subsets based on CSF1R expression

Zeinali, S., Sutton, K., Zefreh, M. G., Mabbott, N. A., & Vervelde, L. (2024) · Scientific Reports · doi:10.1038/s41598-024-59368-x · Cited by 4 · see citing works

Learning immune cell differentiationPreprint

Maslova, A., Ramírez, R. N., Ma, K., Schmutz, H., Wang, C., Fox, C., Ng, B., Benoist, C. O., Mostafavi, S., & the Immunological Genome Project (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2019.12.21.885814 · Cited by 4 · see citing works

scSAGRN: Inferring gene regulatory networks from single-cell multi-omics using spatial association

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Downregulated Smad3 signaling impairs the maturation of MO-MDSC in colorectal cancer

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Redistribution of PU.1 partner transcription factor RUNX1 binding secures cell survival during leukemogenesis

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TNFα Rescues Dendritic Cell Development in Hematopoietic Stem and Progenitor Cells Lacking C/EBPα

Subramanian, A., Rosenberger, A., Schwarzenberger, E., Schaefer, C., Strobl, H., Zebisch, A., Sill, H., & Wölfler, A. (2020) · Cells · doi:10.3390/cells9051223 · Cited by 3 · see citing works

The AML-associated K313 mutation enhances C/EBPα activity by leading to C/EBPα overexpression

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The Histone Chaperone CAF-1 Sustains Myeloid Lineage IdentityPreprint

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RNA activation of CEBPA improves leukemia treatment

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Single-cell transcriptome analysis profiles the enlarged subsets of myeloid-biased HSPCs with preleukemic characters in disuse osteoporosis mice

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Role of CEBPa in trophectoderm competence installment

Wei, X., Salvador‐Martínez, I., Meglicki, M., Plana-Carmona, M., Klonizakis, A., Pernaute, B., Irimia, M., Stik, G., Popovic, M., Garcia, G. T., et al. (2025) · Science Advances · doi:10.1126/sciadv.ady1693 · Cited by 1 · see citing works

Dissecting microglial contributions to neurodegenerative disease pathophysiology using human pluripotent stem cells

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Dual regulation of NFS1 by TRIM67-mediated degradation and CEBPA-driven transcription modulates colorectal cancer progression

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DNMT/G9a Complex Inhibition Uncovers Epigenetic Vulnerabilities and Induces IFN-Response in Acute Myeloid LeukemiaPreprint

Schönefeld, A., Zanetti, C., Schmitt, E. C., Woods, K., Westerback, A., Mitsch, S. M., Rühle, F., Kelekçi, S., Fol, L., Shah, V., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.12.11.627891 · Cited by 1 · see citing works

Path of differentiation defines human macrophage identityPreprint

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scTELL: A Single-Cell ATAC-seq Tool for Locus-Specific Transposable Element Identification in Chromatin AccessibilityPreprint

Jeong, K., Ha, H., Xing, J., Choi, J., & Kim, K. (2025) · Research Square · doi:10.21203/rs.3.rs-6574738/v1 · Cited by 1 · see citing works

Non-coding variants impact cis -regulatory coordination in a cell type-specific mannerPreprint

Pushkarev, O., van Mierlo, G., Kribelbauer-Swietek, J. F., Saelens, W., Gardeux, V., & Deplancke, B. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.10.11.561870

Prediction of context-specific regulatory programs and pathways using interpretable deep learningPreprint

Doncevic, D., Alvarez, C. R., Li, A., Zhang, Y., Bachmann, A., Noack, K., & Herrmann, C. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.11.06.622202

Additional file 1 of Non-coding variants impact cis-regulatory coordination in a cell type-specific manner

Pushkarev, O., van Mierlo, G., Kribelbauer, J. F., Saelens, W., Gardeux, V., & Deplancke, B. (2024) · Figshare · doi:10.6084/m9.figshare.26333222

Additional file 5 of Non-coding variants impact cis-regulatory coordination in a cell type-specific manner

Pushkarev, O., van Mierlo, G., Kribelbauer, J. F., Saelens, W., Gardeux, V., & Deplancke, B. (2024) · Figshare · doi:10.6084/m9.figshare.26750699

Additional file 6 of Non-coding variants impact cis-regulatory coordination in a cell type-specific manner

Pushkarev, O., van Mierlo, G., Kribelbauer, J. F., Saelens, W., Gardeux, V., & Deplancke, B. (2024) · Figshare · doi:10.6084/m9.figshare.26750702

Additional file 2 of Non-coding variants impact cis-regulatory coordination in a cell type-specific manner

Pushkarev, O., van Mierlo, G., Kribelbauer, J. F., Saelens, W., Gardeux, V., & Deplancke, B. (2024) · Figshare · doi:10.6084/m9.figshare.26333392

Additional file 7 of Non-coding variants impact cis-regulatory coordination in a cell type-specific manner

Pushkarev, O., van Mierlo, G., Kribelbauer, J. F., Saelens, W., Gardeux, V., & Deplancke, B. (2024) · Figshare · doi:10.6084/m9.figshare.26750705

Additional file 4 of Non-coding variants impact cis-regulatory coordination in a cell type-specific manner

Pushkarev, O., van Mierlo, G., Kribelbauer, J. F., Saelens, W., Gardeux, V., & Deplancke, B. (2024) · Figshare · doi:10.6084/m9.figshare.26750696

Additional file 9 of Non-coding variants impact cis-regulatory coordination in a cell type-specific manner

Pushkarev, O., van Mierlo, G., Kribelbauer, J. F., Saelens, W., Gardeux, V., & Deplancke, B. (2024) · Figshare · doi:10.6084/m9.figshare.26750711

Additional file 3 of Non-coding variants impact cis-regulatory coordination in a cell type-specific manner

Pushkarev, O., van Mierlo, G., Kribelbauer, J. F., Saelens, W., Gardeux, V., & Deplancke, B. (2024) · Figshare · doi:10.6084/m9.figshare.26750693

Additional file 1 of Aging aggravates acetaminophen-induced acute liver injury and inflammation through inordinate C/EBPα-BMP9 crosstalk

Liu, R., Xu, W., Zhu, H., Dong, Z., Dong, H., & Yin, S. (2024) · Figshare · doi:10.6084/m9.figshare.26576288

Additional file 8 of Non-coding variants impact cis-regulatory coordination in a cell type-specific manner

Pushkarev, O., van Mierlo, G., Kribelbauer, J. F., Saelens, W., Gardeux, V., & Deplancke, B. (2024) · Figshare · doi:10.6084/m9.figshare.26750708

Single-cell multi-omic profiling of lung immune cells identifies novel asthma risk genes and cell-type specific functionsPreprint

Gu, J., Decker, D. C., Zhong, X., Sperling, A. I., Ober, C., Nóbrega, M. A., He, X., & Schoettler, N. (2026) · Research Square · doi:10.21203/rs.3.rs-8914109/v1

scTELL: a single-cell ATAC-seq tool for locus-specific transposable element identification in chromatin accessibility

Jeong, K., Ha, H. H., Xing, J., Choi, J., & Kim, K. (2026) · Mobile DNA · doi:10.1186/s13100-026-00395-y

BARTsc identifies key transcriptional regulators from single-cell omics dataPreprint

Zhang, H., Kang, L., Wang, J., Liang, K., Wang, Z., Xu, K., & Zang, C. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.02.24.707729

Ciblage thérapeutique de la protéine CDK6 dans les leucémies aiguës myéloïdes

Brault, L. M. (2022) · theses.fr (ABES) · doi:10.70675/26bca708z5a9az4d80z85bfz9159b330b1e8

A Multi-modal LLM-Knowledge Fusion Framework for Predicting Single-cell Genetic Perturbation EffectsPreprint

Lu, M., You, N., Zhang, H., Zheng, L., Li, B., Jiang, W., Zhang, Y., Sun, H., & Zhou, Y. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.04.24.720560 · Cited by 1 · see citing works

Regulatory architecture underlying immune dysregulation reconstructed by single-cell multi-omics in lupus nephritisPreprint

Zhao, H., Yang, F., Chen, T., Zhang, J., Shi, J., Liu, X., Chen, S., Ma, Z., Liu, S., Fu, X., et al. (2026) · medRxiv · doi:10.64898/2026.05.06.26352515

The Onset of Myeloid Differentiation in Hematopoietic Progenitors In Vivo is Coordinated with S-phase ProgressionPreprint

Metz, J., Greco, A., Frank, L., Claudino, N., Rodewald, H.-R., & Höfer, T. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.05.10.724120

PTPRJ Drives Clonal Selection in CEBPA-mutated AMLPreprint

Lubin, A., Hockings, C., Hoade, Y., Copper, L., Dace, P., Hayes, E., Tambaku, T., Hill, M., Bhamra, A., Seinkmane, E., et al. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.07.07.736996

Bcl11a orchestrates multilineage integrity in aging hematopoiesis by regulating multipotent progenitor fate decisions

Zhang, L., Xu, X., Wang, J., Cui, X., Wang, C., & Yu, Y. (2026) · Cell Reports · doi:10.1016/j.celrep.2026.117716 · Cited by 1 · see citing works

FLT3-ITD signals for CEBPA and p53 proteolysis by the ubiquitin-proteosome pathwayPreprint

Saunthararajah, Y., Gu, X., Biswas, S., Zahran, Z. A. M., Bae, S., Balusu, R., Jha, B. K., & Maciejewski, J. P. (2026) · Research Square · doi:10.21203/rs.3.rs-10436387/v1

Cell-cycle control of chromatin creates a therapeutic window for epigenetic therapy in tumorsPreprint

Hayatigolkhatmi, K., Valzelli, R., Ceccacci, E., Hosseini, A., Menna, O. E., Romanenghi, M., Pallavicini, I., Soda, E., Ejlli, O., Villa, E., et al. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.09.03.748889

TCDD traps long-term hematopoietic stem cells and skews myeloid commitment in ex vivo mouse bone marrow

Chan, W. Y., Ting, W. H., & Chu, W. C. K. (2026) · Journal of Hazardous Materials Advances · doi:10.1016/j.hazadv.2026.101637

An autonomous CEBPA enhancer specific for myeloid-lineage priming and neutrophilic differentiation

Avellino, R., Havermans, M., Erpelinck-Verschueren, C. A. J., Sanders, M. A., Hoogenboezem, R. M., van de Werken, H. J. G., Rombouts, E. J. C., van Lom, K., van Strien, P. M. H., Gebhard, C., et al. (2016) · Blood · doi:10.1182/blood-2016-01-695759 · Cited by 82 · see citing works

Regulation of the myeloperoxidase enhancer binding proteins Pu1, C-EBP alpha, -beta, and -delta during granulocyte-lineage specification.

Ford, A. M., Bennett, C. L., Healy, L. E., Towatari, M., Greaves, M. F., & Enver, T. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.20.10838 · Cited by 133 · see citing works

Identification of a Novel CEBPE Enhancer Essential for Granulocytic Differentiation

Shyamsunder, P., Shanmugasundaram, M., Mayakonda, A., Teoh, W. W., Han, L., Lim, M. C., Fullwood, M. J., An, Ö., Yang, H. H., Shi, J., et al. (2018) · Blood · doi:10.1182/blood-2018-99-116091

Identification of a novel enhancer of CEBPE essential for granulocytic differentiation

Shyamsunder, P., Shanmugasundaram, M., Mayakonda, A., Dakle, P., Teoh, W. W., Han, L., Kanojia, D., Lim, M. C., Fullwood, M. J., An, Ö., et al. (2019) · Blood · doi:10.1182/blood.2018886077 · Cited by 62 · see citing works

The regulatory control of Cebpa enhancers and silencers in the myeloid and red-blood cell lineages

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