Maxwell, Patrick H.

Autosomal dominant erythrocytosis and pulmonary arterial hypertension associated with an activating HIF2α mutation

Gale, D. P., Harten, S. K., Reid, C. D. L., Tuddenham, E. G. D., & Maxwell, P. H. (2008) · Blood

Erythropoietin and Anemia TreatmentPulmonary Hypertension Research and Treatments

Cited by 157

Deletion of the von Hippel–Lindau gene in pancreatic β cells impairs glucose homeostasis in mice

Cantley, J., Selman, C., Shukla, D., Abramov, A. Y., Forstreuter, F., Esteban, M. A., Claret, M., Lingard, S. J., Clements, M., Harten, S. K., et al. (2008) · Journal of Clinical Investigation

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 127

Osteocytic oxygen sensing controls bone mass through epigenetic regulation of sclerostin

Stegen, S., Stockmans, I., Moermans, K., Thienpont, B., Maxwell, P. H., Carmeliet, P., & Carmeliet, G. (2018) · Nature Communications

Bone Metabolism and DiseasesBone health and osteoporosis research

Cited by 126

The hypoxia response pathway and β ‐cell function

Cantley, J., Grey, S. T., Maxwell, P. H., & Withers, D. J. (2010) · Diabetes, Obesity and Metabolism

Pancreatic function and diabetesCancer, Hypoxia, and Metabolism

Cited by 119

The use of dioxygen by HIF prolyl hydroxylase (PHD1)

McNeill, L. A., Hewitson, K. S., Gleadle, J. M., Horsfall, L. E., Oldham, N. J., Maxwell, P. H., Pugh, C. W., Ratcliffe, P. J., & Schofield, C. J. (2002) · Bioorganic & Medicinal Chemistry Letters

Metal-Catalyzed Oxygenation MechanismsCancer, Hypoxia, and Metabolism

Cited by 116

AI education for clinicians

Schubert, T., Oosterlinck, T., Stevens, R. D., Maxwell, P. H., & van der Schaar, M. (2025) · eClinicalMedicine

Artificial Intelligence in Healthcare and EducationInnovations in Medical Education

Cited by 103

Evidence for a lack of a direct transcriptional suppression of the iron regulatory peptide hepcidin by hypoxia-inducible factors

Volke, M., Gale, D. P., Maegdefrau, U., Schley, G., Klanke, B., Bosserhoff, A.-K., Maxwell, P. H., Eckardt, K.-U., & Warnecke, C. (2009) · PLoS ONE

Iron Metabolism and DisordersErythropoietin and Anemia Treatment

Cited by 93

Cardiopulmonary function in two human disorders of the hypoxia‐inducible factor (HIF) pathway: von Hippel‐Lindau disease and HIF‐2α gain‐of‐function mutation

Formenti, F., Beer, P. A., Croft, Q. P. P., Dorrington, K. L., Gale, D. P., Lappin, T. R. J., Lucas, G. S., Maher, E. R., Maxwell, P. H., McMullin, M. F., et al. (2011) · The FASEB Journal

Cancer, Hypoxia, and MetabolismPulmonary Hypertension Research and Treatments

Cited by 92

A spatiotemporal atlas of mouse liver homeostasis and regeneration

Xu, J., Guo, P., Hao, S., Shangguan, S., Shi, Q., Volpe, G., Huang, K., Zuo, J., An, J., Yuan, Y., et al. (2024) · Nature Genetics

Liver physiology and pathologySingle-cell and spatial transcriptomics

Cited by 75

Distinct novel mutations affecting the same base in the NIPA1 gene cause autosomal dominant hereditary spastic paraplegia in two Chinese families

Chen, S., Song, C., Guo, H., Xu, P., Huang, W., Zhou, Y., Sun, J., Li, C., Du, Y., Li, X., et al. (2005) · Human Mutation

Hereditary Neurological DisordersGenetic Neurodegenerative Diseases

Cited by 61

The Hypoxia-inducible Factor Renders Cancer Cells More Sensitive to Vitamin C-induced Toxicity

Tian, W., Wang, Y., Xu, Y., Guo, X., Wang, B., Sun, L., Liu, L., Cui, F., Zhuang, Q., Bao, X., et al. (2014) · Journal of Biological Chemistry

Cancer, Hypoxia, and MetabolismVitamin C and Antioxidants Research

Cited by 59

Factor inhibiting HIF (FIH-1) promotes renal cancer cell survival by protecting cells from HIF-1α-mediated apoptosis

Khan, M. N., Bhattacharyya, T., Andrikopoulos, P., Esteban, M. A., Barod, R., Connor, T., Ashcroft, M., Maxwell, P. H., & Kiriakidis, S. (2011) · British Journal of Cancer

Cancer, Hypoxia, and MetabolismRenal cell carcinoma treatment

Cited by 40