Casini, Antonio

A highly specific SpCas9 variant is identified by in vivo screening in yeast

Casini, A., Olivieri, M., Petris, G., Montagna, C., Reginato, G., Maule, G., Lorenzin, F., Prandi, D., Romanel, A., Demichelis, F., et al. (2018) · Nature Biotechnology

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 493

Editing a γ-globin repressor binding site restores fetal hemoglobin synthesis and corrects the sickle cell disease phenotype

Weber, L., Frati, G., Felix, T., Hardouin, G., Casini, A., Wollenschlaeger, C., Meneghini, V., Masson, C., De Cian, A., Chalumeau, A., et al. (2020) · Science Advances

Hemoglobinopathies and Related DisordersCRISPR and Genetic Engineering

Cited by 140

VSV-G-Enveloped Vesicles for Traceless Delivery of CRISPR-Cas9

Montagna, C., Petris, G., Casini, A., Maule, G., Franceschini, G. M., Zanella, I., Conti, L., Arnoldi, F., Burrone, O. R., Zentilin, L., et al. (2018) · Molecular Therapy Nucleic Acids

CRISPR and Genetic EngineeringRNA Interference and Gene Delivery

Cited by 117

Hit and go CAS9 delivered through a lentiviral based self-limiting circuit

Petris, G., Casini, A., Montagna, C., Lorenzin, F., Prandi, D., Romanel, A., Zasso, J., Conti, L., Demichelis, F., & Cereseto, A. (2017) · Nature Communications

CRISPR and Genetic EngineeringVirus-based gene therapy research

Cited by 98

Allele specific repair of splicing mutations in cystic fibrosis through AsCas12a genome editing

Maule, G., Casini, A., Montagna, C., Ramalho, A. S., De Boeck, K., Debyser, Z., Carlon, M. S., Petris, G., & Cereseto, A. (2019) · Nature Communications

CRISPR and Genetic EngineeringCystic Fibrosis Research Advances

Cited by 86

Eukaryotic-driven directed evolution of Cas9 nucleases

Ruta, G. V., Ciciani, M., Kheir, E., Gentile, M. D., Amistadi, S., Casini, A., & Cereseto, A. (2023) · Genome biology

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 15