Klockgether, Thomas

Second consensus statement on the diagnosis of multiple system atrophy

Gilman, S., Wenning, G. K., Low, P. A., Brooks, D. J., Mathias, C. J., Trojanowski, J. Q., Wood, N. W., Colosimo, C., Dürr, A., Fowler, C. J., et al. (2008) · Neurology

Parkinson's Disease Mechanisms and TreatmentsNeurological diseases and metabolism

Cited by 3,140

Scale for the assessment and rating of ataxia: Development of a new clinical scale

Schmitz-Hübsch, T., du Montcel, S. T., Baliko, L., Berciano, J., Boesch, S., Depondt, C., Giunti, P., Globas, C., Infante, J., Kang, J. S., et al. (2006) · Neurology

Genetic Neurodegenerative DiseasesBalance, Gait, and Falls Prevention

Cited by 1,967

Acute treatment with the PPARγ agonist pioglitazone and ibuprofen reduces glial inflammation and Aβ1–42 levels in APPV717I transgenic mice

Heneka, M. T., Sastre, M., Dumitrescu-Ozimek, L., Hanke, A., Dewachter, I., Kuiperi, C., O'Banion, K., Klockgether, T., Van Leuven, F., & Landreth, G. E. (2005) · Brain

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 565

Contribution of inflammatory processes to Alzheimer's disease: molecular mechanisms

Sastre, M., Klockgether, T., & Heneka, M. T. (2006) · International Journal of Developmental Neuroscience

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 426

Nonsteroidal anti-inflammatory drugs repress β-secretase gene promoter activity by the activation of PPARγ

Sastre, M., Dewachter, I., Rossner, S., Bogdanovic, N., Rosen, E., Borghgraef, P., Evert, B. O., Dumitrescu-Ozimek, L., Thal, D. R., Landreth, G., et al. (2006) · Proceedings of the National Academy of Sciences

Alzheimer's disease research and treatmentsPeroxisome Proliferator-Activated Receptors

Cited by 373

Nitration of Tyrosine 10 Critically Enhances Amyloid β Aggregation and Plaque Formation

Kummer, M. P., Hermes, M., Delekarte, A., Hammerschmidt, T., Kumar, S., Terwel, D., Walter, J., Pape, H.-C., König, S., Roeber, S., et al. (2011) · Neuron

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 336

Hereditary spastic paraplegia: Clinicogenetic lessons from 608 patients

Schüle, R., Wiethoff, S., Martus, P., Karle, K. N., Otto, S., Klebe, S., Klimpe, S., Gallenmüller, C., Kurzwelly, D., Henkel, D., et al. (2016) · Annals of Neurology

Hereditary Neurological DisordersGenetic Neurodegenerative Diseases

Cited by 315

Focal glial activation coincides with increased BACE1 activation and precedes amyloid plaque deposition in APP[V717I] transgenic mice

Heneka, M. T., Sastre, M., Dumitrescu-Ozimek, L., Dewachter, I., Walter, J., Klockgether, T., & Van Leuven, F. (2005) · Journal of Neuroinflammation

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 309

Locus Ceruleus Degeneration Promotes Alzheimer Pathogenesis in Amyloid Precursor Protein 23 Transgenic Mice

Heneka, M. T., Ramanathan, M., Jacobs, A. H., Dumitrescu-Ozimek, L., Bilkei-Gorzo, A., Debeir, T., Sastre, M., Galldiks, N., Zimmer, A., Hoehn, M., et al. (2006) · The Journal of Neuroscience

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 305

Bright light therapy in Parkinson's disease: a pilot study

Paus, S., Schmitz‐Hübsch, T., Wüllner, U., Vogel, A., Klockgether, T., & Abele, M. (2007) · Movement Disorders

Parkinson's Disease Mechanisms and TreatmentsCircadian rhythm and melatonin

Cited by 162

Peroxisome proliferator-activated receptor gamma agonists protect cerebellar granule cells from cytokine-induced apoptotic cell death by inhibition of inducible nitric oxide synthase

Heneka, M. T., L. Feinstein, D., Galea, E., Gleichmann, M., Wüllner, U., & Klockgether, T. (1999) · Journal of Neuroimmunology

Peroxisome Proliferator-Activated ReceptorsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 150

Molecular Analysis of the PTEN, TP53 and CDKN2A Tumor Suppressor Genes in Long-term Survivors of Glioblastoma Multiforme

Kraus, J. A., Glesmann, N., Beck, M., Krex, D., Klockgether, T., Schackert, G., & Schlegel, U. (2000) · Journal of Neuro-Oncology

Glioma Diagnosis and TreatmentCancer-related Molecular Pathways

Cited by 100

Genes involved in hereditary ataxias

Klockgether, T. (1998) · Trends in Neurosciences

Genetic Neurodegenerative DiseasesHereditary Neurological Disorders

Cited by 83

Creatine has no beneficial effect on skeletal muscle energy metabolism in patients with single mitochondrial DNA deletions: a placebo‐controlled, double‐blind 31P‐MRS crossover study

Kornblum, C., Schröder, R., Müller, K., Vorgerd, M., Eggers, J., Bogdanow, M., Papassotiropoulos, A., Fabian, K., Klockgether, T., & Zange, J. (2005) · European Journal of Neurology

Mitochondrial Function and PathologyMuscle metabolism and nutrition

Cited by 65

Elevated in vivo [18F]‐AV‐1451 uptake in a patient with progressive supranuclear palsy

Hammes, J., Bischof, G. N., Giehl, K., Faber, J., Drzezga, A., Klockgether, T., & van Eimeren, T. (2017) · Movement Disorders

Parkinson's Disease Mechanisms and TreatmentsAlzheimer's disease research and treatments

Cited by 49

Tau and neurofilament light‐chain as fluid biomarkers in spinocerebellar ataxia type 3

Garcia‐Moreno, H., Prudencio, M., Thomas‐Black, G., Solanky, N., Jansen‐West, K. R., Hanna AL‐Shaikh, R., Heslegrave, A., Zetterberg, H., Santana, M. M., Pereira de Almeida, L., et al. (2022) · European Journal of Neurology

Genetic Neurodegenerative DiseasesAmyotrophic Lateral Sclerosis Research

Cited by 49

Quantitative proteomics of synaptosome S‐nitrosylation in Alzheimer’s disease

Wijasa, T. S., Sylvester, M., Brocke‐Ahmadinejad, N., Schwartz, S., Santarelli, F., Gieselmann, V., Klockgether, T., Brosseron, F., & Heneka, M. T. (2020) · Journal of Neurochemistry

Alzheimer's disease research and treatmentsRedox biology and oxidative stress

Cited by 41

Identification of inhibitor‐of‐differentiation 2 (Id2) as a modulator of neuronal apoptosis

Gleichmann, M., Buchheim, G., El‐Bizri, H., Yokota, Y., Klockgether, T., Kügler, S., Bähr, M., Weller, M., & Schulz, J. B. (2002) · Journal of Neurochemistry

Cell death mechanisms and regulationNeurogenesis and neuroplasticity mechanisms

Cited by 35

Methionine metabolism and phenotypic variability in X-linked adrenoleukodystrophy

Linnebank, M., Kemp, S., Wanders, R. J. A., Kleijer, W. J., van der Sterre, M. L. T., Gärtner, J., Fliessbach, K., Semmler, A., Sokolowski, P., Köhler, W., et al. (2006) · Neurology

Metabolism and Genetic DisordersHereditary Neurological Disorders

Cited by 22

Genetic variations and humoral immune responses to myelin oligodendroglia glycoprotein in adult phenotypes of X-linked adrenoleukodystrophy

Schmidt, S., Marrosu, G. M., Kölsch, H., Haase, C. G., Ferenczik, S., Sokolowski, P., Köhler, W., Schmidt, M., Papassotiropoulos, A., Heun, R., et al. (2003) · Journal of Neuroimmunology

Multiple Sclerosis Research StudiesLysosomal Storage Disorders Research

Cited by 8