Uziel, Tamar

A Single Ataxia Telangiectasia Gene with a Product Similar to PI-3 Kinase

Savitsky, K., Bar-Shira, A., Gilad, S., Rotman, G., Ziv, Y., Vanagaite, L., Tagle, D. A., Smith, S., Uziel, T., Sfez, S., et al. (1995) · Science

DNA Repair MechanismsCancer-related Molecular Pathways

Cited by 2,785

Requirement of the MRN complex for ATM activation by DNA damage

Uziel, T., Lerenthal, Y., Moyal, L., Andegeko, Y., Mittelman, L., & Shiloh, Y. (2003) · The EMBO Journal

DNA Repair MechanismsEffects of Radiation Exposure

Cited by 1,075

Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours

Lasko, L. M., Jakob, C. G., Edalji, R. P., Qiu, W., Montgomery, D., Digiammarino, E. L., Hansen, T. M., Risi, R. M., Frey, R., Manaves, V., et al. (2017) · Nature

Histone Deacetylase Inhibitors ResearchProtein Degradation and Inhibitors

Cited by 858

Selective inhibition of the BD2 bromodomain of BET proteins in prostate cancer

Faivre, E. J., McDaniel, K. F., Albert, D. H., Mantena, S. R., Plotnik, J. P., Wilcox, D., Zhang, L., Bui, M. H., Sheppard, G. S., Wang, L., et al. (2020) · Nature

Protein Degradation and InhibitorsProstate Cancer Treatment and Research

Cited by 408

Venetoclax increases intratumoral effector T cells and antitumor efficacy in combination with immune checkpoint blockade

Kohlhapp, F. J., Haribhai, D., Mathew, R., Duggan, R., Ellis, P. A., Wang, R., Lasater, E. A., Shi, Y., Dave, N., Riehm, J. J., et al. (2021) · Cancer Discovery

Cancer Immunotherapy and BiomarkersCell death mechanisms and regulation

Cited by 126

Ataxia-telangiectasia: chronic activation of damage-responsive functions is reduced by α-lipoic acid

Gatei, M., Shkedy, D., Khanna, K. K., Uziel, T., Shiloh, Y., Pandita, T. K., Lavin, M. F., & Rotman, G. (2001) · Oncogene

DNA Repair MechanismsEffects of Radiation Exposure

Cited by 68