Yaqoob, Usman

Mechanical Stretch Increases Expression of CXCL1 in Liver Sinusoidal Endothelial Cells to Recruit Neutrophils, Generate Sinusoidal Microthombi, and Promote Portal Hypertension

Hilscher, M. B., Sehrawat, T., Arab, J. P., Zeng, Z., Gao, J., Liu, M., Kostallari, E., Gao, Y., Simonetto, D. A., Yaqoob, U., et al. (2019) · Gastroenterology

Liver physiology and pathologyLiver Disease and Transplantation

Cited by 240

P300 Acetyltransferase Mediates Stiffness-Induced Activation of Hepatic Stellate Cells Into Tumor-Promoting Myofibroblasts

Dou, C., Liu, Z., Tu, K., Zhang, H., Chen, C., Yaqoob, U., Wang, Y., Wen, J., van Deursen, J., Sicard, D., et al. (2018) · Gastroenterology

Liver physiology and pathologyCellular Mechanics and Interactions

Cited by 240

Hepatic stellate cell–derived platelet‐derived growth factor receptor‐alpha‐enriched extracellular vesicles promote liver fibrosis in mice through SHP2

Kostallari, E., Hirsova, P., Prasnicka, A., Verma, V. K., Yaqoob, U., Wongjarupong, N., Roberts, L. R., & Shah, V. H. (2018) · Hepatology

Liver physiology and pathologyExtracellular vesicles in disease

Cited by 111

Endothelial p300 Promotes Portal Hypertension and Hepatic Fibrosis Through C‐C Motif Chemokine Ligand 2–Mediated Angiocrine Signaling

Gao, J., Wei, B., Liu, M., Hirsova, P., Sehrawat, T. S., Cao, S., Hu, X., Xue, F., Yaqoob, U., Kang, N., et al. (2021) · Hepatology

Liver physiology and pathologyLiver Disease and Transplantation

Cited by 100

Mechanotransduction-induced glycolysis epigenetically regulates a CXCL1-dominant angiocrine signaling program in liver sinusoidal endothelial cells in vitro and in vivo

Greuter, T., Yaqoob, U., Gan, C., Jalan-Sakrikar, N., Kostallari, E., Lu, J., Gao, J., Sun, L., Liu, M., Sehrawat, T. S., et al. (2022) · Journal of Hepatology

Cellular Mechanics and InteractionsLiver physiology and pathology

Cited by 92

Enhancer of Zeste Homologue 2 Inhibition Attenuates TGF-β Dependent Hepatic Stellate Cell Activation and Liver Fibrosis

Martin-Mateos, R., De Assuncao, T. M., Arab, J. P., Jalan-Sakrikar, N., Yaqoob, U., Greuter, T., Verma, V. K., Mathison, A. J., Cao, S., Lomberk, G., et al. (2019) · Cellular and Molecular Gastroenterology and Hepatology

Liver physiology and pathologyLiver Disease Diagnosis and Treatment

Cited by 73

Glycolysis in hepatic stellate cells coordinates fibrogenic extracellular vesicle release spatially to amplify liver fibrosis

Khanal, S., Liu, Y., Bamidele, A. O., Wixom, A. Q., Washington, A. M., Jalan-Sakrikar, N., Cooper, S. A., Vuckovic, I., Zhang, S., Zhong, J., et al. (2024) · Science Advances

Liver physiology and pathologyExtracellular vesicles in disease

Cited by 41

Liver sinusoidal endothelial cells contribute to portal hypertension through collagen type IV–driven sinusoidal remodeling

Gan, C., Yaqoob, U., Lu, J., Xie, M., Anwar, A., Jalan-Sakrikar, N., Jerez, S., Sehrawat, T. S., Navarro-Corcuera, A., Kostallari, E., et al. (2024) · JCI Insight

Liver physiology and pathologyLiver Disease and Transplantation

Cited by 21