Macaulay, Iain C.

Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia

Brann, D. H., Tsukahara, T., Weinreb, C., Lipovsek, M., Van den Berge, K., Gong, B., Chance, R., Macaulay, I. C., Chou, H.-J., Fletcher, R. B., et al. (2020) · Science Advances

Olfactory and Sensory Function StudiesSARS-CoV-2 and COVID-19 Research

Cited by 1,198

G&T-seq: parallel sequencing of single-cell genomes and transcriptomes

Macaulay, I. C., Haerty, W., Kumar, P., Li, Y. I., Hu, T. X., Teng, M. J., Goolam, M., Saurat, N., Coupland, P., Shirley, L. M., et al. (2015) · Nature Methods

Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies

Cited by 750

Parallel single-cell sequencing links transcriptional and epigenetic heterogeneity

Angermueller, C., Clark, S. J., Lee, H. J., Macaulay, I. C., Teng, M. J., Hu, T. X., Krueger, F., Smallwood, S. A., Ponting, C. P., Voet, T., et al. (2016) · Nature Methods

Epigenetics and DNA MethylationSingle-cell and spatial transcriptomics

Cited by 717

Power analysis of single-cell RNA-sequencing experiments

Svensson, V., Natarajan, K. N., Ly, L.-H., Miragaia, R. J., Labalette, C., Macaulay, I. C., Cvejic, A., & Teichmann, S. A. (2017) · Nature Methods

Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies

Cited by 568

Heterogeneity in Oct4 and Sox2 Targets Biases Cell Fate in 4-Cell Mouse Embryos

Goolam, M., Scialdone, A., Graham, S. J. L., Macaulay, I. C., Jedrusik, A., Hupalowska, A., Voet, T., Marioni, J. C., & Zernicka-Goetz, M. (2016) · Cell

Pluripotent Stem Cells ResearchDevelopmental Biology and Gene Regulation

Cited by 484

Combined Single-Cell Functional and Gene Expression Analysis Resolves Heterogeneity within Stem Cell Populations

Wilson, N. K., Kent, D. G., Buettner, F., Shehata, M., Macaulay, I. C., Calero-Nieto, F. J., Sánchez Castillo, M., Oedekoven, C. A., Diamanti, E., Schulte, R., et al. (2015) · Cell Stem Cell

Hematopoietic Stem Cell TransplantationSingle-cell and spatial transcriptomics

Cited by 466

Single-cell multiomics: multiple measurements from single cells

Macaulay, I. C., Ponting, C. P., & Voet, T. (2017) · Trends in Genetics

Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies

Cited by 451

Single Cell Genomics: Advances and Future Perspectives

Macaulay, I. C., & Voet, T. (2014) · PLoS Genetics

Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies

Cited by 384

Decoding the regulatory network of early blood development from single-cell gene expression measurements

Moignard, V., Woodhouse, S., Haghverdi, L., Lilly, A. J., Tanaka, Y., Wilkinson, A. C., Buettner, F., Macaulay, I. C., Jawaid, W., Diamanti, E., et al. (2015) · Nature Biotechnology

Gene Regulatory Network AnalysisSingle-cell and spatial transcriptomics

Cited by 380

Resolving early mesoderm diversification through single-cell expression profiling

Scialdone, A., Tanaka, Y., Jawaid, W., Moignard, V., Wilson, N. K., Macaulay, I. C., Marioni, J. C., & Göttgens, B. (2016) · Nature

Developmental Biology and Gene RegulationPluripotent Stem Cells Research

Cited by 293

Single-Cell RNA-Sequencing Reveals a Continuous Spectrum of Differentiation in Hematopoietic Cells

Macaulay, I. C., Svensson, V., Labalette, C., Ferreira, L., Hamey, F., Voet, T., Teichmann, S. A., & Cvejic, A. (2016) · Cell Reports

Single-cell and spatial transcriptomicsDevelopmental Biology and Gene Regulation

Cited by 191

The earliest thymic T cell progenitors sustain B cell and myeloid lineage potential

Luc, S., Luis, T. C., Boukarabila, H., Macaulay, I. C., Buza-Vidas, N., Bouriez-Jones, T., Lutteropp, M., Woll, P. S., Loughran, S. J., Mead, A. J., et al. (2012) · Nature Immunology

T-cell and B-cell ImmunologyHematopoietic Stem Cell Transplantation

Cited by 152

Acute myeloid leukemia induces protumoral p16INK4a-driven senescence in the bone marrow microenvironment

Abdul-Aziz, A. M., Sun, Y., Hellmich, C., Marlein, C. R., Mistry, J., Forde, E., Piddock, R. E., Shafat, M. S., Morfakis, A., Mehta, T., et al. (2019) · Blood

Telomeres, Telomerase, and SenescenceAcute Myeloid Leukemia Research

Cited by 105

Into the multiverse: advances in single-cell multiomic profiling

Ogbeide, S., Giannese, F., Mincarelli, L., & Macaulay, I. C. (2022) · Trends in Genetics

Single-cell and spatial transcriptomicsGenomics and Chromatin Dynamics

Cited by 82