Farrer, Lindsay A.

Effects of Multiple Genetic Loci on Age at Onset in Late-Onset Alzheimer Disease: A Genome-Wide Association Study

Naj, A. C., Jun, G., Reitz, C., Kunkle, B. W., Perry, W., Park, Y. S., Beecham, G. W., Rajbhandary, R. A., Hamilton-Nelson, K. L., Wang, L.-S., et al. (2014) · JAMA Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 185

Genome-wide association study of the rate of cognitive decline in Alzheimer’s disease

Sherva, R., Tripodis, Y., Bennett, D. A., Chibnik, L. B., Crane, P. K., de Jager, P. L., Farrer, L. A., Saykin, A. J., Shulman, J. M., Naj, A., et al. (2014) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 180

BCL11A is a major HbF quantitative trait locus in three different populations with β-hemoglobinopathies

Sedgewick, A. E., Timofeev, N., Sebastiani, P., So, J. C. C., Ma, E. S. K., Chan, L. C., Fucharoen, G., Fucharoen, S., Barbosa, C. G., Vardarajan, B. N., et al. (2008) · Blood Cells, Molecules, and Diseases

Hemoglobinopathies and Related DisordersGenetic Associations and Epidemiology

Cited by 172

Diabetes mellitus in Huntington disease

Farrer, L. A. (1985) · Clinical Genetics

Genetic Neurodegenerative DiseasesPrion Diseases and Protein Misfolding

Cited by 170

Polygenic Overlap Between C-Reactive Protein, Plasma Lipids, and Alzheimer Disease

Desikan, R. S., Schork, A. J., Wang, Y., Thompson, W. K., Dehghan, A., Ridker, P. M., Chasman, D. I., McEvoy, L. K., Holland, D., Chen, C.-H., et al. (2015) · Circulation

Alzheimer's disease research and treatmentsGenetic Associations and Epidemiology

Cited by 154

A rare mutation in UNC5C predisposes to late-onset Alzheimer's disease and increases neuronal cell death

Alzheimer's Disease Genetics Consortium, Wetzel-Smith, M. K., Hunkapiller, J., Bhangale, T. R., Srinivasan, K., Maloney, J. A., Atwal, J. K., Sa, S. M., B Yaylaoglu, M., Foreman, O., et al. (2014) · Nature Medicine

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 153

Dissecting the genetic relationship between cardiovascular risk factors and Alzheimer’s disease

Broce, I. J., Tan, C. H., Fan, C. C., Jansen, I., Savage, J. E., Witoelar, A., Wen, N., Hess, C. P., Dillon, W. P., Glastonbury, C. M., et al. (2019) · Acta Neuropathologica

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 140

Two rare AKAP9 variants are associated with Alzheimer's disease in African Americans

Logue, M. W., Schu, M., Vardarajan, B. N., Farrell, J., Bennett, D. A., Buxbaum, J. D., Byrd, G. S., Ertekin‐Taner, N., Evans, D., Foroud, T., et al. (2014) · Alzheimer's & Dementia

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 136

Evidence of CNIH3 involvement in opioid dependence

Nelson, E. C., Agrawal, A., Heath, A. C., Bogdan, R., Sherva, R., Zhang, B., Al-Hasani, R., Bruchas, M. R., Chou, Y.-L., Demers, C. H., et al. (2016) · Molecular Psychiatry

Neurotransmitter Receptor Influence on BehaviorGenetic Associations and Epidemiology

Cited by 131

Effects of Age, Sex, and Ethnicity on the Association Between Apolipoprotein E Genotype and Alzheimer Disease: A Meta-analysis

Farrer, L. A. (1997) · JAMA

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 124

Follow-up of loci from the International Genomics of Alzheimer’s Disease Project identifies TRIP4 as a novel susceptibility gene

Ruiz, A., Heilmann, S., Becker, T., Hernández, I., Wagner, H., Thelen, M., Mauleón, A., Rosende-Roca, M., Bellenguez, C., Bis, J. C., et al. (2014) · Translational Psychiatry

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 97

Genetic Risk Variants Associated With Comorbid Alcohol Dependence and Major Depression

Zhou, H., Polimanti, R., Yang, B.-Z., Wang, Q., Han, S., Sherva, R., Nuñez, Y. Z., Zhao, H., Farrer, L. A., Kranzler, H. R., et al. (2017) · JAMA Psychiatry

Genetic Associations and EpidemiologySubstance Abuse Treatment and Outcomes

Cited by 94

Genome-wide meta-analysis reveals common splice site acceptor variant in CHRNA4 associated with nicotine dependence

Hancock, D. B., Reginsson, G. W., Gaddis, N. C., Chen, X., Saccone, N. L., Lutz, S. M., Qaiser, B., Sherva, R., Steinberg, S., Zink, F., et al. (2015) · Translational Psychiatry

Smoking Behavior and CessationGenetic Associations and Epidemiology

Cited by 85

APOE Promoter Polymorphism-219T/G is an Effect Modifier of the Influence of APOE ε4 on Alzheimer’s Disease Risk in a Multiracial Sample

Choi, K., Lee, J., Gunasekaran, T., Kang, S., Lee, W., Jeong, J., Lim, H., Zhang, X., Zhu, C., Won, S.-Y., et al. (2019) · Journal of Clinical Medicine

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 72

Association of Polymorphisms in the Angiotensin-Converting Enzyme Gene with Alzheimer Disease in an Israeli Arab Community

Meng, Y., Baldwin, C. T., Bowirrat, A., Waraska, K., Inzelberg, R., Friedland, R. P., & Farrer, L. A. (2006) · The American Journal of Human Genetics

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 72

Association of APOE Genotypes and Chronic Traumatic Encephalopathy

Atherton, K., Han, X., Chung, J., Cherry, J. D., Baucom, Z., Saltiel, N., Nair, E., Abdolmohammadi, B., Uretsky, M., Khan, M. M., et al. (2022) · JAMA Neurology

Traumatic Brain Injury ResearchAlzheimer's disease research and treatments

Cited by 70

African ancestry GWAS of dementia in a large military cohort identifies significant risk loci

Sherva, R., Zhang, R., Sahelijo, N., Jun, G., Anglin, T., Chanfreau, C., Cho, K., Fonda, J. R., Gaziano, J. M., Harrington, K. M., et al. (2023) · Molecular Psychiatry

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 68

Genome‐wide association study of Alzheimer's disease endophenotypes at prediagnosis stages

Chung, J., Wang, X., Maruyama, T., Ma, Y., Zhang, X., Mez, J., Sherva, R., Takeyama, H., Initiative, T. A. D. N., Lunetta, K. L., et al. (2018) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 67

PLXNA4 is associated with Alzheimer disease and modulates tau phosphorylation

Jun, G., Asai, H., Zeldich, E., Drapeau, E., Chen, C., Chung, J., Park, J., Kim, S., Haroutunian, V., Foroud, T., et al. (2014) · Annals of Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 67

Midlife lipid and glucose levels are associated with Alzheimer's disease

Zhang, X., Tong, T., Chang, A., Ang, T. F. A., Tao, Q., Auerbach, S., Devine, S., Qiu, W. Q., Mez, J., Massaro, J., et al. (2023) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 65

A transcriptome-wide association study based on 27 tissues identifies 106 genes potentially relevant for disease pathology in age-related macular degeneration

Strunz, T., Lauwen, S., Kiel, C., International AMD Genomics Consortium (IAMDGC), Fritsche, L. G., Igl, W., Bailey, J. N. C., Grassmann, F., Sengupta, S., Bragg-Gresham, J. L., et al. (2020) · Scientific Reports

Genetic Associations and EpidemiologyRetinal Diseases and Treatments

Cited by 60

A Common Variant of IL-6R is Associated with Elevated IL-6 Pathway Activity in Alzheimer’s Disease Brains

Haddick, P. C. G., Alzheimer’s Disease Genetic Consortium (ADGC), A. D. N. I. (., Larson, J. L., Rathore, N., Bhangale, T. R., Phung, Q. T., Srinivasan, K., Hansen, D. V., Lill, J. R., Pericak-Vance, M. A., et al. (2017) · Journal of Alzheimer's Disease

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 55

Genome‐wide association study of rate of cognitive decline in Alzheimer's disease patients identifies novel genes and pathways

Sherva, R., Gross, A., Mukherjee, S., Koesterer, R., Amouyel, P., Bellenguez, C., Dufouil, C., Bennett, D. A., Chibnik, L., Cruchaga, C., et al. (2020) · Alzheimer's & Dementia

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 54

Report of the APOE4 National Institute on Aging/Alzheimer Disease Sequencing Project Consortium Working Group: Reducing APOE4 in Carriers is a Therapeutic Goal for Alzheimer’s Disease

Vance, J. M., Farrer, L. A., Huang, Y., Cruchaga, C., Hyman, B. T., Pericak‐Vance, M. A., Goate, A. M., Greicius, M. D., Griswold, A. J., Haines, J. L., et al. (2024) · Annals of Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 52