Edgar, James R.

Tetherin is an exosomal tether

Edgar, J. R., Manna, P. T., Nishimura, S., Banting, G., & Robinson, M. S. (2016) · eLife

Extracellular vesicles in diseaseCellular transport and secretion

Cited by 161

Frontotemporal dementia caused by CHMP2B mutation is characterised by neuronal lysosomal storage pathology

The FReJA consortium, Clayton, E. L., Mizielinska, S., Edgar, J. R., Nielsen, T. T., Marshall, S., Norona, F. E., Robbins, M., Damirji, H., Holm, I. E., et al. (2015) · Acta Neuropathologica

Lysosomal Storage Disorders ResearchAlzheimer's disease research and treatments

Cited by 96

Aβ accumulation causes MVB enlargement and is modelled by dominant negative VPS4A

Willén, K., Edgar, J. R., Hasegawa, T., Tanaka, N., Futter, C. E., & Gouras, G. K. (2017) · Molecular Neurodegeneration

Alzheimer's disease research and treatmentsCellular transport and secretion

Cited by 86

ESCRTs regulate amyloid precursor protein sorting in multivesicular bodies and intracellular beta amyloid accumulation

Edgar, J. R., Willén, K., Gouras, G. K., & Futter, C. E. (2015) · Journal of Cell Science

Alzheimer's disease research and treatmentsCellular transport and secretion

Cited by 70

Contribution of the clathrin adaptor AP-1 subunit µ1 to acidic cluster protein sorting

Navarro Negredo, P., Edgar, J. R., Wrobel, A. G., Zaccai, N. R., Antrobus, R., Owen, D. J., & Robinson, M. S. (2017) · Journal of Cell Biology

Cellular transport and secretionHIV Research and Treatment

Cited by 50

Encephalomyocarditis virus protein 2B* interacts with 14-3-3 proteins through a phosphorylated C-terminal binding motif

Nguyen, S. K., Anders, N., Holmes, S., Barrow, H. G., Lukhovitskaya, N., Jahun, A. S., Georgana, I., Caller, L. G., Edgar, J. R., Graham, S. C., et al. (2025) · mBio

14-3-3 protein interactionsAnimal Virus Infections Studies

Cited by 5