Puram, Rishi V.

Generation of mouse models of myeloid malignancy with combinatorial genetic lesions using CRISPR-Cas9 genome editing

Heckl, D., Kowalczyk, M. S., Yudovich, D., Belizaire, R., Puram, R. V., McConkey, M. E., Thielke, A., Aster, J. C., Regev, A., & Ebert, B. L. (2014) · Nature Biotechnology

CRISPR and Genetic EngineeringAcute Myeloid Leukemia Research

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Transcriptional silencing of γ-globin by BCL11A involves long-range interactions and cooperation with SOX6

Xu, J., Sankaran, V. G., Ni, M., Menne, T. F., Puram, R. V., Kim, W., & Orkin, S. H. (2010) · Genes & Development

Hemoglobinopathies and Related DisordersGenomics and Chromatin Dynamics

Cited by 361

Core circadian clock genes regulate leukemia stem cells in AML

Puram, R. V., Kowalczyk, M. S., de Boer, C. G., Schneider, R. K., Miller, P. G., McConkey, M., Tothova, Z., Tejero, H., Heckl, D., Järås, M., et al. (2016) · Cell

Circadian rhythm and melatoninAcute Myeloid Leukemia Research

Cited by 274

Csnk1a1 inhibition has p53-dependent therapeutic efficacy in acute myeloid leukemia

Järås, M., Miller, P. G., Chu, L. P., Puram, R. V., Fink, E. C., Schneider, R. K., Al-Shahrour, F., Peña, P., Breyfogle, L. J., Hartwell, K. A., et al. (2014) · Journal of Experimental Medicine

Acute Myeloid Leukemia ResearchCancer-related Molecular Pathways

Cited by 92