Sai, Jiqing

Drugging an undruggable pocket on KRAS

Kessler, D., Gmachl, M., Mantoulidis, A., Martin, L. J., Zoephel, A., Mayer, M., Gollner, A., Covini, D., Fischer, S., Gerstberger, T., et al. (2019) · Proceedings of the National Academy of Sciences

Protein Kinase Regulation and GTPase SignalingProtein Tyrosine Phosphatases

Cited by 449

PI3K inhibition reduces mammary tumor growth and facilitates antitumor immunity and anti-PD1 responses

Sai, J., Owens, P., Novitskiy, S. V., Hawkins, O. E., Vilgelm, A. E., Yang, J., Sobolik, T., Lavender, N., Johnson, A. C., McClain, C., et al. (2017) · Clinical Cancer Research

PI3K/AKT/mTOR signaling in cancerCancer Immunotherapy and Biomarkers

Cited by 138

Discovery and Optimization of Salicylic Acid-Derived Sulfonamide Inhibitors of the WD Repeat-Containing Protein 5–MYC Protein–Protein Interaction

Macdonald, J. D., Chacón Simon, S., Han, C., Wang, F., Shaw, J. G., Howes, J. E., Sai, J., Yuh, J. P., Camper, D., Alicie, B. M., et al. (2019) · Journal of Medicinal Chemistry

Computational Drug Discovery MethodsHeterocyclic Compound Synthesis and Bioactivity

Cited by 66

The IL sequence in the LLKIL motif in CXCR2 is required for full ligand-induced activation of Erk, Akt, and chemotaxis in HL60 cells

Sai, J., Walker, G., Wikswo, J., & Richmond, A. (2006) · Journal of Biological Chemistry

Chemokine receptors and signalingReceptor Mechanisms and Signaling

Cited by 56