Brem, Reto

Oxidative stress-induced protein damage inhibits DNA repair and determines mutation risk and therapeutic efficacy

McAdam, E., Brem, R., & Karran, P. (2016) · Molecular Cancer Research

DNA Repair MechanismsSkin Protection and Aging

Cited by 86

Multiple forms of DNA Damage Caused by UVA Photoactivation of DNA 6‐Thioguanine

Brem, R., & Karran, P. (2012) · Photochemistry and Photobiology

Carcinogens and Genotoxicity AssessmentSkin Protection and Aging

Cited by 76

Reactive oxygen species generated by thiopurine/UVA cause irreparable transcription-blocking DNA lesions

Brem, R., Li, F., & Karran, P. (2009) · Nucleic Acids Research

DNA Repair MechanismsSkin Protection and Aging

Cited by 67

Oxidative damage to RPA limits the nucleotide excision repair capacity of human cells

Guven, M., Brem, R., Macpherson, P., Peacock, M., & Karran, P. (2015) · Journal of Investigative Dermatology

DNA Repair MechanismsSkin Protection and Aging

Cited by 61

Efficient DNA interstrand crosslinking by 6-thioguanine and UVA radiation

Brem, R., Daehn, I., & Karran, P. (2011) · DNA Repair

DNA Repair MechanismsCarcinogens and Genotoxicity Assessment

Cited by 48

The methyl methanesulfonate induced S-phase delay in XRCC1-deficient cells requires ATM and ATR

Brem, R., Fernet, M., Chapot, B., & Hall, J. (2008) · DNA Repair

DNA Repair MechanismsPARP inhibition in cancer therapy

Cited by 20