Don, Anthony S.

Enhancement of capillary leakage and restoration of lymphocyte egress by a chiral S1P1 antagonist in vivo

Sanna, M. G., Wang, S.-K., Gonzalez-Cabrera, P. J., Don, A., Marsolais, D., Matheu, M. P., Wei, S. H., Parker, I., Jo, E., Cheng, W.-C., et al. (2006) · Nature Chemical Biology

Sphingolipid Metabolism and SignalingLymphatic System and Diseases

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Loss of the neuroprotective factor sphingosine 1-phosphate early in Alzheimer’s disease pathogenesis

Couttas, T. A., Kain, N., Daniels, B., Lim, X. Y., Shepherd, C., Kril, J., Pickford, R., Li, H., Garner, B., & Don, A. S. (2014) · Acta Neuropathologica Communications

Sphingolipid Metabolism and SignalingAlzheimer's disease research and treatments

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Oligodendroglial fatty acid metabolism as a central nervous system energy reserve

Asadollahi, E., Trevisiol, A., Saab, A. S., Looser, Z. J., Dibaj, P., Ebrahimi, R., Kusch, K., Ruhwedel, T., Möbius, W., Jahn, O., et al. (2024) · Nature Neuroscience

Lipid metabolism and biosynthesisNeurogenesis and neuroplasticity mechanisms

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Altered lipid levels provide evidence for myelin dysfunction in multiple system atrophy

Don, A. S., Hsiao, J.-H. T., Bleasel, J. M., Couttas, T. A., Halliday, G. M., & Kim, W. S. (2014) · Acta Neuropathologica Communications

Parkinson's Disease Mechanisms and TreatmentsMultiple Sclerosis Research Studies

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Disrupted myelin lipid metabolism differentiates frontotemporal dementia caused by GRN and C9orf72 gene mutations

Marian, O. C., Teo, J. D., Lee, J. Y., Song, H., Kwok, J. B., Landin-Romero, R., Halliday, G., & Don, A. S. (2023) · Acta Neuropathologica Communications

Amyotrophic Lateral Sclerosis ResearchLysosomal Storage Disorders Research

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Sphingosine kinase 2 potentiates amyloid deposition but protects against hippocampal volume loss and demyelination in a mouse model of Alzheimer’s disease

Lei, M., Teo, J. D., Song, H., McEwen, H. P., Yup Lee, J., Couttas, T. A., Duncan, T., Chesworth, R., Bertz, J., Przybyla, M., et al. (2019) · The Journal of Neuroscience

Alzheimer's disease research and treatmentsSphingolipid Metabolism and Signaling

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Deficient brain GABA metabolism leads to widespread impairments of astrocyte and oligodendrocyte function

Andersen, J. V., Marian, O. C., Qvist, F. L., Westi, E. W., Aldana, B. I., Schousboe, A., Don, A. S., Skotte, N. H., & Wellendorph, P. (2024) · Glia

Metabolism and Genetic DisordersAmino Acid Enzymes and Metabolism

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Contextual fear conditioning is enhanced in mice lacking functional sphingosine kinase 2

Lei, M., Shafique, A., Shang, K., Couttas, T. A., Zhao, H., Don, A. S., & Karl, T. (2017) · Behavioural Brain Research

Sphingolipid Metabolism and SignalingMemory and Neural Mechanisms

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