Kovtonyuk, Larisa V.

Chronic interleukin-1 exposure drives haematopoietic stem cells towards precocious myeloid differentiation at the expense of self-renewal

Pietras, E. M., Mirantes-Barbeito, C., Fong, S., Loeffler, D., Kovtonyuk, L. V., Zhang, S., Lakshminarasimhan, R., Chin, C. P., Techner, J.-M., Will, B., et al. (2016) · Nature Cell Biology

Hematopoietic Stem Cell TransplantationBlood disorders and treatments

Cited by 689

Inflamm-aging of hematopoiesis, hematopoietic stem cells, and the bone marrow microenvironment

Kovtonyuk, L. V., Fritsch, K., Feng, X., Manz, M. G., & Takizawa, H. (2016) · Frontiers in Immunology

Hematopoietic Stem Cell TransplantationBlood disorders and treatments

Cited by 371

IL-1 mediates microbiome-induced inflammaging of hematopoietic stem cells in mice

Kovtonyuk, L. V., Caiado, F., Garcia-Martin, S., Manz, E.-M., Helbling, P., Takizawa, H., Boettcher, S., Al-Shahrour, F., Nombela-Arrieta, C., Slack, E., et al. (2022) · Blood

Hematopoietic Stem Cell TransplantationGenetics, Aging, and Longevity in Model Organisms

Cited by 166

Aging drives Tet2 +/− clonal hematopoiesis via IL-1 signaling

Caiado, F., Kovtonyuk, L. V., Gonullu, N. G., Fullin, J., Boettcher, S., & Manz, M. G. (2023) · Blood

Acute Myeloid Leukemia ResearchHematopoietic Stem Cell Transplantation

Cited by 161

Clonal dynamics after allogeneic haematopoietic cell transplantation

Spencer Chapman, M., Wilk, C. M., Boettcher, S., Mitchell, E., Dawson, K., Williams, N., Müller, J., Kovtonyuk, L., Jung, H., Caiado, F., et al. (2024) · Nature

Hematopoietic Stem Cell TransplantationAcute Myeloid Leukemia Research

Cited by 60