McCoy, Kathy D.

Host microbiota constantly control maturation and function of microglia in the CNS

Erny, D., Hrabě de Angelis, A. L., Jaitin, D., Wieghofer, P., Staszewski, O., David, E., Keren-Shaul, H., Mahlakoiv, T., Jakobshagen, K., Buch, T., et al. (2015) · Nature Neuroscience

Neuroinflammation and Neurodegeneration MechanismsGut microbiota and health

Cited by 3,569

Sex differences in the gut microbiome drive hormone-dependent regulation of autoimmunity

Markle, J. G. M., Frank, D. N., Mortin-Toth, S., Robertson, C. E., Feazel, L. M., Rolle-Kampczyk, U., von Bergen, M., McCoy, K. D., Macpherson, A. J., & Danska, J. S. (2013) · Science

Gut microbiota and healthDiabetes and associated disorders

Cited by 2,025

The Intestinal Microbiota Affect Central Levels of Brain-Derived Neurotropic Factor and Behavior in Mice

Bercik, P., Denou, E., Collins, J., Jackson, W., Lu, J., Jury, J., Deng, Y., Blennerhassett, P., Macri, J., McCoy, K. D., et al. (2011) · Gastroenterology

Gut microbiota and healthGastrointestinal motility and disorders

Cited by 1,748

Microbiome-derived inosine modulates response to checkpoint inhibitor immunotherapy

Mager, L. F., Burkhard, R., Pett, N., Cooke, N. C. A., Brown, K., Ramay, H., Paik, S., Stagg, J., Groves, R. A., Gallo, M., et al. (2020) · Science

Cancer Immunotherapy and BiomarkersGut microbiota and health

Cited by 1,407

The maternal microbiota drives early postnatal innate immune development

Gomez de Agüero, M., Ganal-Vonarburg, S. C., Fuhrer, T., Rupp, S., Uchimura, Y., Li, H., Steinert, A., Heikenwalder, M., Hapfelmeier, S., Sauer, U., et al. (2016) · Science

Gut microbiota and healthIL-33, ST2, and ILC Pathways

Cited by 1,231

Intestinal Bacterial Colonization Induces Mutualistic Regulatory T Cell Responses

Geuking, M. B., Cahenzli, J., Lawson, M. A. E., Ng, D. C. K., Slack, E., Hapfelmeier, S., McCoy, K. D., & Macpherson, A. J. (2011) · Immunity

T-cell and B-cell ImmunologyGut microbiota and health

Cited by 840

Reversible Microbial Colonization of Germ-Free Mice Reveals the Dynamics of IgA Immune Responses

Hapfelmeier, S., Lawson, M. A. E., Slack, E., Kirundi, J. K., Stoel, M., Heikenwalder, M., Cahenzli, J., Velykoredko, Y., Balmer, M. L., Endt, K., et al. (2010) · Science

Gut microbiota and healthT-cell and B-cell Immunology

Cited by 835

Intestinal Microbial Diversity during Early-Life Colonization Shapes Long-Term IgE Levels

Cahenzli, J., Köller, Y., Wyss, M., Geuking, M. B., & McCoy, K. D. (2013) · Cell Host & Microbe

Gut microbiota and healthFood Allergy and Anaphylaxis Research

Cited by 611

Lung microbiota promotes tolerance to allergens in neonates via PD-L1

Gollwitzer, E. S., Saglani, S., Trompette, A., Yadava, K., Sherburn, R., McCoy, K. D., Nicod, L. P., Lloyd, C. M., & Marsland, B. J. (2014) · Nature Medicine

Asthma and respiratory diseasesT-cell and B-cell Immunology

Cited by 596

The outer mucus layer hosts a distinct intestinal microbial niche

Li, H., Limenitakis, J. P., Fuhrer, T., Geuking, M. B., Lawson, M. A., Wyss, M., Brugiroux, S., Keller, I., Macpherson, J. A., Rupp, S., et al. (2015) · Nature Communications

Gut microbiota and healthMicrobial Community Ecology and Physiology

Cited by 511

The Liver May Act as a Firewall Mediating Mutualism Between the Host and Its Gut Commensal Microbiota

Balmer, M. L., Slack, E., de Gottardi, A., Lawson, M. A. E., Hapfelmeier, S., Miele, L., Grieco, A., Van Vlierberghe, H., Fahrner, R., Patuto, N., et al. (2014) · Science Translational Medicine

Gut microbiota and healthImmune Response and Inflammation

Cited by 470

Dysregulation of Allergic Airway Inflammation in the Absence of Microbial Colonization

Herbst, T., Sichelstiel, A., Schär, C., Yadava, K., Bürki, K., Cahenzli, J., McCoy, K., Marsland, B. J., & Harris, N. L. (2011) · American Journal of Respiratory and Critical Care Medicine

Asthma and respiratory diseasesAllergic Rhinitis and Sensitization

Cited by 440

Crosstalk between B lymphocytes, microbiota and the intestinal epithelium governs immunity versus metabolism in the gut

Shulzhenko, N., Morgun, A., Hsiao, W., Battle, M., Yao, M., Gavrilova, O., Orandle, M., Mayer, L., Macpherson, A. J., McCoy, K. D., et al. (2011) · Nature Medicine

Gut microbiota and healthT-cell and B-cell Immunology

Cited by 349

Immune responses that adapt the intestinal mucosa to commensal intestinal bacteria

Macpherson, A. J., Geuking, M. B., & McCoy, K. D. (2005) · Immunology

Gut microbiota and healthImmune Response and Inflammation

Cited by 283

Microbiota-derived peptide mimics drive lethal inflammatory cardiomyopathy

Gil-Cruz, C., Perez-Shibayama, C., De Martin, A., Ronchi, F., van der Borght, K., Niederer, R., Onder, L., Lütge, M., Novkovic, M., Nindl, V., et al. (2019) · Science

Viral Infections and Immunology ResearchCardiac Fibrosis and Remodeling

Cited by 260

IgA production without μ or δ chain expression in developing B cells

Macpherson, A. J. S., Lamarre, A., McCoy, K., Harriman, G. R., Odermatt, B., Dougan, G., Hengartner, H., & Zinkernagel, R. M. (2001) · Nature Immunology

T-cell and B-cell ImmunologyMonoclonal and Polyclonal Antibodies Research

Cited by 223

ATP-gated ionotropic P2X7 receptor controls follicular T helper cell numbers in Peyer’s patches to promote host-microbiota mutualism

Proietti, M., Cornacchione, V., Rezzonico Jost, T., Romagnani, A., Faliti, C. E., Perruzza, L., Rigoni, R., Radaelli, E., Caprioli, F., Preziuso, S., et al. (2014) · Immunity

Adenosine and Purinergic SignalingT-cell and B-cell Immunology

Cited by 181

Nlrp6- and ASC-Dependent Inflammasomes Do Not Shape the Commensal Gut Microbiota Composition

Mamantopoulos, M., Ronchi, F., Van Hauwermeiren, F., Vieira-Silva, S., Yilmaz, B., Martens, L., Saeys, Y., Drexler, S. K., Yazdi, A. S., Raes, J., et al. (2017) · Immunity

Gut microbiota and healthInflammasome and immune disorders

Cited by 181

Antibodies Set Boundaries Limiting Microbial Metabolite Penetration and the Resultant Mammalian Host Response

Uchimura, Y., Fuhrer, T., Li, H., Lawson, M. A., Zimmermann, M., Yilmaz, B., Zindel, J., Ronchi, F., Sorribas, M., Hapfelmeier, S., et al. (2018) · Immunity

Gut microbiota and healthGastrointestinal motility and disorders

Cited by 153

Commensal and Probiotic Bacteria Influence Intestinal Barrier Function and Susceptibility to Colitis in Nod1−/−;Nod2−/− Mice

Natividad, J. M. M., Petit, V., Huang, X., de Palma, G., Jury, J., Sanz, Y., Philpott, D., Garcia Rodenas, C. L., McCoy, K. D., & Verdu, E. F. (2012) · Inflammatory Bowel Diseases

Gut microbiota and healthInflammatory Bowel Disease

Cited by 139

Kupffer cell–like syncytia replenish resident macrophage function in the fibrotic liver

Peiseler, M., Araujo David, B., Zindel, J., Surewaard, B. G. J., Lee, W.-Y., Heymann, F., Nusse, Y., Castanheira, F. V. S., Shim, R., Guillot, A., et al. (2023) · Science

Liver physiology and pathologyImmune cells in cancer

Cited by 123

T follicular helper cells promote a beneficial gut ecosystem for host metabolic homeostasis by sensing microbiota-derived extracellular ATP

Perruzza, L., Gargari, G., Proietti, M., Fosso, B., D’Erchia, A. M., Faliti, C. E., Rezzonico-Jost, T., Scribano, D., Mauri, L., Colombo, D., et al. (2017) · Cell Reports

Adenosine and Purinergic SignalingGut microbiota and health

Cited by 114

Sex-hormone-driven innate antibodies protect females and infants against EPEC infection

Zeng, Z., Surewaard, B. G. J., Wong, C. H. Y., Guettler, C., Petri, B., Burkhard, R., Wyss, M., Le Moual, H., Devinney, R., Thompson, G. C., et al. (2018) · Nature Immunology

Escherichia coli research studiesComplement system in diseases

Cited by 96

Melanoma and microbiota: Current understanding and future directions

Routy, B., Jackson, T., Mählmann, L., Baumgartner, C. K., Blaser, M., Byrd, A., Corvaia, N., Couts, K., Davar, D., Derosa, L., et al. (2024) · Cancer Cell

Gut microbiota and healthCancer Immunotherapy and Biomarkers

Cited by 89