Lynn, Francis C.

Serotonin regulates pancreatic beta cell mass during pregnancy

Kim, H., Toyofuku, Y., Lynn, F. C., Chak, E., Uchida, T., Mizukami, H., Fujitani, Y., Kawamori, R., Miyatsuka, T., Kosaka, Y., et al. (2010) · Nature Medicine

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 586

MicroRNA Expression Is Required for Pancreatic Islet Cell Genesis in the Mouse

Lynn, F. C., Skewes-Cox, P., Kosaka, Y., McManus, M. T., Harfe, B. D., & German, M. S. (2007) · Diabetes

Pancreatic function and diabetesMicroRNA in disease regulation

Cited by 351

Defective Glucose-Dependent Insulinotropic Polypeptide Receptor Expression in Diabetic Fatty Zucker Rats

Lynn, F. C., Pamir, N., Ng, E. H. C., McIntosh, C. H. S., Kieffer, T. J., & Pederson, R. A. (2001) · Diabetes

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 208

The Polycomb-Dependent Epigenome Controls β Cell Dysfunction, Dedifferentiation, and Diabetes

Lu, T. T.-H., Heyne, S., Dror, E., Casas, E., Leonhardt, L., Boenke, T., Yang, C.-H., Sagar, Arrigoni, L., Dalgaard, K., et al. (2018) · Cell Metabolism

Pancreatic function and diabetesEpigenetics and DNA Methylation

Cited by 151

Reversal of islet GIP receptor down-regulation and resistance to GIP by reducing hyperglycemia in the Zucker rat

Piteau, S., Olver, A., Kim, S.-J., Winter, K., Pospisilik, J. A., Lynn, F., Manhart, S., Demuth, H.-U., Speck, M., Pederson, R. A., et al. (2007) · Biochemical and Biophysical Research Communications

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 130

Glucose-dependent insulinotropic polypeptide receptor null mice exhibit compensatory changes in the enteroinsular axis

Pamir, N., Lynn, F. C., Buchan, A. M. J., Ehses, J., Hinke, S. A., Pospisilik, J. A., Miyawaki, K., Yamada, Y., Seino, Y., McIntosh, C. H. S., et al. (2003) · American Journal of Physiology-Endocrinology and Metabolism

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 126

A novel pathway for regulation of glucose‐dependent insulinotropic polypeptide receptor expression in β‐cells

Lynn, F. C., Thompson, S. A., Pospisilik, J. A., Ehses, J. A., Hinke, S. A., Pamir, N., McIntosh, C. H. S., & Pederson, R. A. (2003) · The FASEB Journal

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 91

Glucose-Dependent Insulinotropic Polypeptide Stimulation of Lipolysis in Differentiated 3T3-L1 Cells: Wortmannin-Sensitive Inhibition by Insulin**This work was supported by grants from Zymogenetics Inc. (Seattle, WA), the Medical Research Council of Canada (5–90007-RAP/CHSM) and the Canadian Diabetes Association (CHSM/RAP).

McIntosh, C. H. S., Bremsak, I., Lynn, F. C., Gill, R., Hinke, S. A., Gelling, R., Nian, C., McKnight, G., Jaspers, S., & Pederson, R. A. (1999) · Endocrinology

Lipid metabolism and biosynthesisAdipose Tissue and Metabolism

Cited by 73

Maintenance of β-Cell Maturity and Plasticity in the Adult Pancreas

Szabat, M., Lynn, F. C., Hoffman, B. G., Kieffer, T. J., Allan, D. W., & Johnson, J. D. (2012) · Diabetes

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 68