Pakshir, Pardis

The big five in fibrosis: Macrophages, myofibroblasts, matrix, mechanics, and miscommunication

Pakshir, P., & Hinz, B. (2018) · Matrix Biology

Wound Healing and TreatmentsLiver physiology and pathology

Cited by 396

The myofibroblast at a glance

Pakshir, P., Noskovicova, N., Lodyga, M., Son, D. O., Schuster, R., Goodwin, A., Karvonen, H., & Hinz, B. (2020) · Journal of Cell Science

Wound Healing and TreatmentsLiver physiology and pathology

Cited by 293

Dynamic fibroblast contractions attract remote macrophages in fibrillar collagen matrix

Pakshir, P., Alizadehgiashi, M., Wong, B., Coelho, N. M., Chen, X., Gong, Z., Shenoy, V. B., McCulloch, C. A., & Hinz, B. (2019) · Nature Communications

Cellular Mechanics and InteractionsWound Healing and Treatments

Cited by 281

Implant Fibrosis and the Underappreciated Role of Myofibroblasts in the Foreign Body Reaction

Noskovicova, N., Hinz, B., & Pakshir, P. (2021) · Cells

Wound Healing and TreatmentsTissue Engineering and Regenerative Medicine

Cited by 184

Cadherin-11–mediated adhesion of macrophages to myofibroblasts establishes a profibrotic niche of active TGF-β

Lodyga, M., Cambridge, E., Karvonen, H. M., Pakshir, P., Wu, B., Boo, S., Kiebalo, M., Kaarteenaho, R., Glogauer, M., Kapoor, M., et al. (2019) · Science Signaling

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisTGF-β signaling in diseases

Cited by 181

Acute contact with profibrotic macrophages mechanically activates fibroblasts via αvβ3 integrin–mediated engagement of Piezo1

Ezzo, M., Spindler, K., Wang, J. B., Lee, D., Pecoraro, G., Cowen, J., Pakshir, P., & Hinz, B. (2024) · Science Advances

Cellular Mechanics and InteractionsWound Healing and Treatments

Cited by 82