Clarke, Paul A.

Patient-derived organoids model treatment response of metastatic gastrointestinal cancers

Vlachogiannis, G., Hedayat, S., Vatsiou, A., Jamin, Y., Fernández-Mateos, J., Khan, K., Lampis, A., Eason, K., Huntingford, I., Burke, R., et al. (2018) · Science

Cancer Cells and MetastasisColorectal Cancer Treatments and Studies

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Kirsten ras mutations in patients with colorectal cancer: The multicenter “RASCAL” study

Andreyev, H. J. N., Norman, A. R., Clarke, P. A., Cunningham, D., & Oates, J. R. (1998) · JNCI Journal of the National Cancer Institute

Colorectal Cancer Treatments and StudiesGenetic factors in colorectal cancer

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Inhibitors of cyclin-dependent kinases as cancer therapeutics.

Whittaker, S. R., Mallinger, A., Workman, P., & Clarke, P. A. (2017) · Pharmacology & Therapeutics

Advanced Breast Cancer TherapiesCancer-related Molecular Pathways

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Dual Targeting of HSC70 and HSP72 Inhibits HSP90 Function and Induces Tumor-Specific Apoptosis

Powers, M. V., Clarke, P. A., & Workman, P. (2008) · Cancer Cell

Heat shock proteins researchCell death mechanisms and regulation

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Structure-Based Optimization of Potent, Selective, and Orally Bioavailable CDK8 Inhibitors Discovered by High-Throughput Screening

Czodrowski, P., Mallinger, A., Wienke, D., Esdar, C., Pöschke, O., Busch, M., Rohdich, F., Eccles, S. A., Ortiz-Ruiz, M.-J., Schneider, R., et al. (2016) · Journal of Medicinal Chemistry

Heterocyclic Compound Synthesis and BioactivityComputational Drug Discovery Methods

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