Loewer, Alexander

Circular RNAs are a large class of animal RNAs with regulatory potency

Memczak, S., Jens, M., Elefsinioti, A., Torti, F., Krueger, J., Rybak, A., Maier, L., Mackowiak, S. D., Gregersen, L. H., Munschauer, M., et al. (2013) · Nature

Circular RNAs in diseasesRNA Research and Splicing

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p53 Dynamics Control Cell Fate

Purvis, J. E., Karhohs, K. W., Mock, C., Batchelor, E., Loewer, A., & Lahav, G. (2012) · Science

Cancer-related Molecular PathwaysGene Regulatory Network Analysis

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Recurrent Initiation: A Mechanism for Triggering p53 Pulses in Response to DNA Damage

Batchelor, E., Mock, C. S., Bhan, I., Loewer, A., & Lahav, G. (2008) · Molecular Cell

Cancer-related Molecular PathwaysDNA Repair Mechanisms

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Cell-to-cell variation in p53 dynamics leads to fractional killing.

Paek, A. L., Liu, J. C., Loewer, A., Forrester, W. C., & Lahav, G. (2016) · Cell

Cancer-related Molecular PathwaysCell death mechanisms and regulation

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Distinct mechanisms act in concert to mediate cell cycle arrest

Toettcher, J. E., Loewer, A., Ostheimer, G. J., Yaffe, M. B., Tidor, B., & Lahav, G. (2009) · Proceedings of the National Academy of Sciences

Cancer-related Molecular PathwaysDNA Repair Mechanisms

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PCNA-Mediated Degradation of p21 Coordinates the DNA Damage Response and Cell Cycle Regulation in Individual Cells

Sheng, C., Mendler, I.-H., Rieke, S., Snyder, P., Jentsch, M., Friedrich, D., Drossel, B., & Loewer, A. (2019) · Cell Reports

Cancer-related Molecular PathwaysDNA Repair Mechanisms

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Transcriptional regulators ensuring specific gene expression and decision-making at high TGFβ doses

Hartmann, L., Kristofori, P., Li, C., Becker, K., Hexemer, L., Bohn, S., Lenhardt, S., Weiss, S., Voss, B., Loewer, A., et al. (2025) · Life Science Alliance

TGF-β signaling in diseasesGene Regulatory Network Analysis

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