Mer, Georges

The BRCT Domain Is a Phospho-Protein Binding Domain

Yu, X., Chini, C. C. S., He, M., Mer, G., & Chen, J. (2003) · Science

DNA Repair MechanismsBRCA gene mutations in cancer

Cited by 862

Acetylation limits 53BP1 association with damaged chromatin to promote homologous recombination

Tang, J., Cho, N. W., Cui, G., Manion, E. M., Shanbhag, N. M., Botuyan, M. V., Mer, G., & Greenberg, R. A. (2013) · Nature Structural & Molecular Biology

DNA Repair MechanismsPARP inhibition in cancer therapy

Cited by 521

Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation

Bian, C., Xu, C., Ruan, J., Lee, K. K., Burke, T. L., Tempel, W., Barsyte, D., Li, J., Wu, M., Zhou, B. O., et al. (2011) · The EMBO Journal

Genomics and Chromatin DynamicsCancer-related gene regulation

Cited by 281

Structural basis for recognition of H3K56-acetylated histone H3–H4 by the chaperone Rtt106

Su, D., Hu, Q., Li, Q., Thompson, J. R., Cui, G., Fazly, A., Davies, B. A., Botuyan, M. V., Zhang, Z., & Mer, G. (2012) · Nature

Genomics and Chromatin DynamicsNuclear Structure and Function

Cited by 128

Celastrol Inhibits Hsp90 Chaperoning of Steroid Receptors by Inducing Fibrillization of the Co-chaperone p23

Chadli, A., Felts, S. J., Wang, Q., Sullivan, W. P., Botuyan, M. V., Fauq, A., Ramirez-Alvarado, M., & Mer, G. (2010) · Journal of Biological Chemistry

Heat shock proteins researchUbiquitin and proteasome pathways

Cited by 94

Lactate accelerates cancer progression through the ERK-GCN5 lactylation-phosphorylation feedback cascade

Yuan, J., Huang, B., Chen, Y., Cui, G., Mer, G., & Zhong, C. (2024) · Nature Chemical Biology

Cancer, Hypoxia, and MetabolismMelanoma and MAPK Pathways

Cited by 26

GCN5–ERK lactylation–phosphorylation loop amplifies lactate-driven cancer progression

Huang, B., Jin, M., Cui, G., Wang, Z., Wang, F., Chen, M., Zhu, L., Li, Y., Yang, X., Li, R., et al. (2026) · Nature Chemical Biology

Cancer, Hypoxia, and MetabolismMelanoma and MAPK Pathways

Cited by 24