Blaauw, Bert

PHD1 controls muscle mTORC1 in a hydroxylation-independent manner by stabilizing leucyl tRNA synthetase

D’Hulst, G., Soro-Arnaiz, I., Masschelein, E., Veys, K., Fitzgerald, G., Smeuninx, B., Kim, S., Deldicque, L., Blaauw, B., Carmeliet, P., et al. (2020) · Nature Communications

Muscle metabolism and nutritionMuscle Physiology and Disorders

Cited by 2,310

Mechanisms regulating skeletal muscle growth and atrophy

Schiaffino, S., Dyar, K. A., Ciciliot, S., Blaauw, B., & Sandri, M. (2013) · The FEBS Journal

Muscle Physiology and DisordersMuscle metabolism and nutrition

Cited by 1,492

Autophagy is required to maintain muscle mass.

Masiero, E., Agatea, L., Mammucari, C., Blaauw, B., Loro, E., Komatsu, M., Metzger, D., Reggiani, C., Schiaffino, S., & Sandri, M. (2009) · Cell Metabolism

Muscle Physiology and DisordersAutophagy in Disease and Therapy

Cited by 1,282

Regulation of autophagy and the ubiquitin-proteasome system by the FoxO transcriptional network during muscle atrophy

Milan, G., Romanello, V., Pescatore, F., Armani, A., Paik, J.-H., Frasson, L., Seydel, A., Zhao, J., Abraham, R., Goldberg, A. L., et al. (2015) · Nature Communications

Muscle Physiology and DisordersFOXO transcription factor regulation

Cited by 709

Age-Associated Loss of OPA1 in Muscle Impacts Muscle Mass, Metabolic Homeostasis, Systemic Inflammation, and Epithelial Senescence

Tezze, C., Romanello, V., Desbats, M. A., Fadini, G. P., Albiero, M., Favaro, G., Ciciliot, S., Soriano, M. E., Morbidoni, V., Cerqua, C., et al. (2017) · Cell Metabolism

Mitochondrial Function and PathologyMuscle Physiology and Disorders

Cited by 568

Autophagy is defective in collagen VI muscular dystrophies, and its reactivation rescues myofiber degeneration

Grumati, P., Coletto, L., Sabatelli, P., Cescon, M., Angelin, A., Bertaggia, E., Blaauw, B., Urciuolo, A., Tiepolo, T., Merlini, L., et al. (2010) · Nature Medicine

Muscle Physiology and DisordersAutophagy in Disease and Therapy

Cited by 540

Smad2 and 3 transcription factors control muscle mass in adulthood

Sartori, R., Milan, G., Patron, M., Mammucari, C., Blaauw, B., Abraham, R., & Sandri, M. (2009) · American Journal of Physiology-Cell Physiology

Muscle Physiology and DisordersTGF-β signaling in diseases

Cited by 517

Collagen VI regulates satellite cell self-renewal and muscle regeneration

Urciuolo, A., Quarta, M., Morbidoni, V., Gattazzo, F., Molon, S., Grumati, P., Montemurro, F., Tedesco, F. S., Blaauw, B., Cossu, G., et al. (2013) · Nature Communications

Muscle Physiology and DisordersNeurogenetic and Muscular Disorders Research

Cited by 511

BMP signaling controls muscle mass

Sartori, R., Schirwis, E., Blaauw, B., Bortolanza, S., Zhao, J., Enzo, E., Stantzou, A., Mouisel, E., Toniolo, L., Ferry, A., et al. (2013) · Nature Genetics

Muscle Physiology and DisordersTGF-β signaling in diseases

Cited by 467

Muscle insulin sensitivity and glucose metabolism are controlled by the intrinsic muscle clock

Dyar, K. A., Ciciliot, S., Wright, L. E., Biensø, R. S., Tagliazucchi, G. M., Patel, V. R., Forcato, M., Paz, M. I. P., Gudiksen, A., Solagna, F., et al. (2014) · Molecular Metabolism

Circadian rhythm and melatoninMetabolism, Diabetes, and Cancer

Cited by 454

Autophagy Impairment in Muscle Induces Neuromuscular Junction Degeneration and Precocious Aging

Carnio, S., LoVerso, F., Baraibar, M. A., Longa, E., Khan, M. M., Maffei, M., Reischl, M., Canepari, M., Loefler, S., Kern, H., et al. (2014) · Cell Reports

Autophagy in Disease and TherapyGenetics, Aging, and Longevity in Model Organisms

Cited by 423

DRP1-mediated mitochondrial shape controls calcium homeostasis and muscle mass

Favaro, G., Romanello, V., Varanita, T., Andrea Desbats, M., Morbidoni, V., Tezze, C., Albiero, M., Canato, M., Gherardi, G., De Stefani, D., et al. (2019) · Nature Communications

Mitochondrial Function and PathologyMuscle Physiology and Disorders

Cited by 398

Signalling pathways regulating muscle mass in ageing skeletal muscle. The role of the IGF1-Akt-mTOR-FoxO pathway

Sandri, M., Barberi, L., Bijlsma, A. Y., Blaauw, B., Dyar, K. A., Milan, G., Mammucari, C., Meskers, C. G. M., Pallafacchina, G., Paoli, A., et al. (2013) · Biogerontology

Muscle Physiology and DisordersMuscle metabolism and nutrition

Cited by 340

Transcription Factor EB Controls Metabolic Flexibility during Exercise

Mansueto, G., Armani, A., Viscomi, C., D’Orsi, L., De Cegli, R., Polishchuk, E. V., Lamperti, C., Di Meo, I., Romanello, V., Marchet, S., et al. (2017) · Cell Metabolism

Metabolism, Diabetes, and CancerAutophagy in Disease and Therapy

Cited by 314

Inducible activation of Akt increases skeletal muscle mass and force without satellite cell activation

Blaauw, B., Canato, M., Agatea, L., Toniolo, L., Mammucari, C., Masiero, E., Abraham, R., Sandri, M., Schiaffino, S., & Reggiani, C. (2009) · The FASEB Journal

Muscle Physiology and DisordersMuscle metabolism and nutrition

Cited by 244

Fibroblast growth factor 21 controls mitophagy and muscle mass

Oost, L. J., Kustermann, M., Armani, A., Blaauw, B., & Romanello, V. (2019) · Journal of Cachexia, Sarcopenia and Muscle

Fibroblast Growth Factor ResearchMuscle Physiology and Disorders

Cited by 231

Defects of Vps15 in skeletal muscles lead to autophagic vacuolar myopathy and lysosomal disease

Nemazanyy, I., Blaauw, B., Paolini, C., Caillaud, C., Protasi, F., Mueller, A., Proikas‐Cezanne, T., Russell, R. C., Guan, K., Nishino, I., et al. (2013) · EMBO Molecular Medicine

Autophagy in Disease and TherapyGlycogen Storage Diseases and Myoclonus

Cited by 126

Reactivation of autophagy by spermidine ameliorates the myopathic defects of collagen VI-null mice

Chrisam, M., Pirozzi, M., Castagnaro, S., Blaauw, B., Polishchuck, R., Cecconi, F., Grumati, P., & Bonaldo, P. (2015) · Autophagy

Muscle Physiology and DisordersAutophagy in Disease and Therapy

Cited by 101

Inhibition of the Fission Machinery Mitigates OPA1 Impairment in Adult Skeletal Muscles

Romanello, V., Scalabrin, M., Albiero, M., Blaauw, B., Scorrano, L., & Sandri, M. (2019) · Cells

Mitochondrial Function and PathologyMuscle Physiology and Disorders

Cited by 91

Skeletal muscle mTORC1 regulates neuromuscular junction stability

Baraldo, M., Geremia, A., Pirazzini, M., Nogara, L., Solagna, F., Türk, C., Nolte, H., Romanello, V., Megighian, A., Boncompagni, S., et al. (2020) · Journal of Cachexia, Sarcopenia and Muscle

Muscle Physiology and DisordersMuscle metabolism and nutrition

Cited by 76

Skeletal Muscle-Specific Methyltransferase METTL21C Trimethylates p97 and Regulates Autophagy-Associated Protein Breakdown

Wiederstein, J. L., Nolte, H., Günther, S., Piller, T., Baraldo, M., Kostin, S., Bloch, W., Schindler, N., Sandri, M., Blaauw, B., et al. (2018) · Cell Reports

Muscle Physiology and DisordersAutophagy in Disease and Therapy

Cited by 52