Tang, Guomei

Loss of mTOR-Dependent Macroautophagy Causes Autistic-like Synaptic Pruning Deficits

Tang, G., Gudsnuk, K., Kuo, S.-H., Cotrina, M. L., Rosoklija, G., Sosunov, A., Sonders, M. S., Kanter, E., Castagna, C., Yamamoto, A., et al. (2014) · Neuron

Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research

Cited by 1,146

Cargo recognition failure is responsible for inefficient autophagy in Huntington’s disease

Martinez-Vicente, M., Talloczy, Z., Wong, E., Tang, G., Koga, H., Kaushik, S., de Vries, R., Arias, E., Harris, S., Sulzer, D., et al. (2010) · Nature Neuroscience

Genetic Neurodegenerative DiseasesAutophagy in Disease and Therapy

Cited by 885

Mitochondrial abnormalities in temporal lobe of autistic brain

Tang, G., Gutierrez Rios, P., Kuo, S.-H., Akman, H. O., Rosoklija, G., Tanji, K., Dwork, A., Schon, E. A., DiMauro, S., Goldman, J., et al. (2013) · Neurobiology of Disease

Autism Spectrum Disorder ResearchMitochondrial Function and Pathology

Cited by 194

Mutant glucocerebrosidase impairs α-synuclein degradation by blockade of chaperone-mediated autophagy

Kuo, S.-H., Tasset, I., Cheng, M. M., Diaz, A., Pan, M.-K., Lieberman, O. J., Hutten, S. J., Alcalay, R. N., Kim, S., Ximénez-Embún, P., et al. (2022) · Science Advances

Lysosomal Storage Disorders ResearchParkinson's Disease Mechanisms and Treatments

Cited by 153

Roles for neuronal and glial autophagy in synaptic pruning during development

Lieberman, O. J., McGuirt, A. F., Tang, G., & Sulzer, D. (2019) · Neurobiology of Disease

Neuroscience and Neuropharmacology ResearchAutophagy in Disease and Therapy

Cited by 87

Huntington disease oligodendrocyte maturation deficits revealed by single-nucleus RNAseq are rescued by thiamine-biotin supplementation

Lim, R. G., Al-Dalahmah, O., Wu, J., Gold, M. P., Reidling, J. C., Tang, G., Adam, M., Dansu, D. K., Park, H.-J., Casaccia, P., et al. (2022) · Nature Communications

Genetic Neurodegenerative DiseasesNeurogenesis and neuroplasticity mechanisms

Cited by 84