Kaplowitz, Neil

EASL Clinical Practice Guidelines: Drug-induced liver injury

Andrade, R. J., Aithal, G. P., Björnsson, E. S., Kaplowitz, N., Kullak-Ublick, G. A., Larrey, D., & Karlsen, T. H. (2019) · Journal of Hepatology

Drug-Induced Hepatotoxicity and ProtectionLiver Diseases and Immunity

Cited by 1,276

Idiosyncratic drug hepatotoxicity

Kaplowitz, N. (2005) · Nature Reviews Drug Discovery

Drug-Induced Hepatotoxicity and ProtectionPharmacovigilance and Adverse Drug Reactions

Cited by 1,054

Features and outcomes of 899 patients with drug-induced liver injury: the DILIN Prospective Study

Chalasani, N., Bonkovsky, H. L., Fontana, R., Lee, W., Stolz, A., Talwalkar, J., Reddy, K. R., Watkins, P. B., Navarro, V., Barnhart, H., et al. (2015) · Gastroenterology

Drug-Induced Hepatotoxicity and ProtectionPharmacovigilance and Adverse Drug Reactions

Cited by 925

Drug-induced liver injury

Andrade, R. J., Chalasani, N., Björnsson, E. S., Suzuki, A., Kullak-Ublick, G. A., Watkins, P. B., Devarbhavi, H., Merz, M., Lucena, M. I., Kaplowitz, N., et al. (2019) · Nature Reviews Disease Primers

Drug-Induced Hepatotoxicity and ProtectionPharmacovigilance and Adverse Drug Reactions

Cited by 924

Role of JNK translocation to mitochondria leading to inhibition of mitochondria bioenergetics in acetaminophen-induced liver injury

Hanawa, N., Shinohara, M., Saberi, B., Gaarde, W. A., Han, D., & Kaplowitz, N. (2008) · Journal of Biological Chemistry

Drug-Induced Hepatotoxicity and ProtectionMitochondrial Function and Pathology

Cited by 527

C-Jun N-terminal kinase plays a major role in murine acetaminophen hepatotoxicity

Gunawan, B. K., Liu, Z., Han, D., Hanawa, N., Gaarde, W. A., & Kaplowitz, N. (2006) · Gastroenterology

Drug-Induced Hepatotoxicity and ProtectionLiver physiology and pathology

Cited by 471

Mechanisms of drug-induced liver injury

Yuan, L., & Kaplowitz, N. (2013) · Clinics in Liver Disease

Drug-Induced Hepatotoxicity and ProtectionLiver physiology and pathology

Cited by 322

Outcome of acute idiosyncratic drug-induced liver injury: Long-term follow-up in a hepatotoxicity registry

Andrade, R. J., Lucena, I. M., Kaplowitz, N., García-Muņoz, B., Borraz, Y., Pachkoria, K., García-Cortés, M., Fernández, C. M., Pelaez, G., Rodrigo, L., et al. (2006) · Hepatology

Drug-Induced Hepatotoxicity and ProtectionPharmacovigilance and Adverse Drug Reactions

Cited by 309

c-Jun N-terminal kinase (JNK)-dependent acute liver injury from acetaminophen or tumor necrosis factor (TNF) requires mitochondrial Sab protein expression in mice

Win, S., Than, T. A., Han, D., Petrovic, L. M., & Kaplowitz, N. (2011) · Journal of Biological Chemistry

Drug-Induced Hepatotoxicity and ProtectionLiver physiology and pathology

Cited by 197

Protein kinase C (PKC) participates in acetaminophen hepatotoxicity through c-jun-N-terminal kinase (JNK)-dependent and -independent signaling pathways

Saberi, B., Ybanez, M. D., Johnson, H. S., Gaarde, W. A., Han, D., & Kaplowitz, N. (2014) · Hepatology

Drug-Induced Hepatotoxicity and ProtectionLiver physiology and pathology

Cited by 88

Mitochondrial GSH determines the toxic or therapeutic potential of superoxide scavenging in steatohepatitis

Montfort, C. V., Matias, N., Fernandez, A., Fucho, R., de la Rosa, L. C., Martinez-Chantar, M. L., Mato, J. M., Machida, K., Tsukamoto, H., Murphy, M. P., et al. (2012) · Journal of Hepatology

Redox biology and oxidative stressDrug-Induced Hepatotoxicity and Protection

Cited by 83

Intestinal Epithelial Chemokine (C-C Motif) Ligand 7 Overexpression Enhances Acetaminophen-Induced Hepatotoxicity in Mice

Niu, M., Luo, Z., Gong, S., Win, S., Kaplowitz, N., Jiang, Y., & Chen, P. (2020) · The American Journal of Pathology

Drug-Induced Hepatotoxicity and ProtectionLiver physiology and pathology

Cited by 26