Mathotaarachchi, Sulantha

Microglial activation and tau propagate jointly across Braak stages

Pascoal, T. A., Benedet, A. L., Ashton, N. J., Kang, M. S., Therriault, J., Chamoun, M., Savard, M., Lussier, F. Z., Tissot, C., Karikari, T. K., et al. (2021) · Nature Medicine

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 490

Association of Apolipoprotein E ε4 With Medial Temporal Tau Independent of Amyloid-β

Therriault, J., Benedet, A. L., Pascoal, T. A., Mathotaarachchi, S., Chamoun, M., Savard, M., Thomas, E., Kang, M. S., Lussier, F., Tissot, C., et al. (2020) · JAMA Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 256

Cerebrospinal fluid p-tau231 as an early indicator of emerging pathology in Alzheimer's disease

Ashton, N. J., Benedet, A. L., Pascoal, T. A., Karikari, T. K., Lantero-Rodriguez, J., Brum, W. S., Mathotaarachchi, S., Therriault, J., Savard, M., Chamoun, M., et al. (2022) · eBioMedicine

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 184

Identifying incipient dementia individuals using machine learning and amyloid imaging

Mathotaarachchi, S., Pascoal, T. A., Shin, M., Benedet, A. L., Kang, M. S., Beaudry, T., Fonov, V. S., Gauthier, S., & Rosa-Neto, P. (2017) · Neurobiology of Aging

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 118

APOEε4 potentiates the relationship between amyloid-β and tau pathologies

Therriault, J., Benedet, A. L., Pascoal, T. A., Mathotaarachchi, S., Savard, M., Chamoun, M., Thomas, E., Kang, M. S., Lussier, F., Tissot, C., et al. (2021) · Molecular Psychiatry

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 105

Synergistic interaction between amyloid and tau predicts the progression to dementia

Pascoal, T. A., Mathotaarachchi, S., Shin, M., Benedet, A. L., Mohades, S., Wang, S., Beaudry, T., Kang, M. S., Soucy, J., Labbe, A., et al. (2017) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 101

Association of plasma P-tau181 with memory decline in non-demented adults

Therriault, J., Benedet, A. L., Pascoal, T. A., Lussier, F. Z., Tissot, C., Karikari, T. K., Ashton, N. J., Chamoun, M., Bezgin, G., Mathotaarachchi, S., et al. (2021) · Brain Communications

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 56

[11C]Martinostat PET analysis reveals reduced HDAC I availability in Alzheimer’s disease

Pascoal, T. A., Chamoun, M., Lax, E., Wey, H.-Y., Shin, M., Ng, K. P., Kang, M. S., Mathotaarachchi, S., Benedet, A. L., Therriault, J., et al. (2022) · Nature Communications

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 43

Constrained instruments and their application to Mendelian randomization with pleiotropy

Jiang, L., Oualkacha, K., Didelez, V., Ciampi, A., Rosa‐Neto, P., Benedet, A. L., Mathotaarachchi, S., Richards, J. B., Greenwood, C. M. T., & Initiative, A. F. T. A. D. N. (2019) · Genetic Epidemiology

Genetic Associations and EpidemiologyAdvanced Causal Inference Techniques

Cited by 23